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1.3.8.6: glutaryl-CoA dehydrogenase (ETF)

This is an abbreviated version!
For detailed information about glutaryl-CoA dehydrogenase (ETF), go to the full flat file.

Word Map on EC 1.3.8.6

Reaction

(E)-glutaconyl-CoA
=
crotonyl-CoA
+
CO2

Synonyms

decarboxylating glutaryl-coenzyme A dehydrogenase, EC 1.3.99.7, GCD, GCDH, GDH, GDHGeo, glutaryl coenzyme A dehydrogenase, glutaryl-CoA dehydrogenase, glutaryl-coenzyme A dehydrogenase, More

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.6 glutaryl-CoA dehydrogenase (ETF)

Inhibitors

Inhibitors on EC 1.3.8.6 - glutaryl-CoA dehydrogenase (ETF)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-pentynoyl-CoA
3-Butynoylpantetheine
-
irreversible
3-Pentynoylpantetheine
-
irreversible
3-thiaglutaryl-CoA
non-oxidizable analogue, which competes with 2-pentynoyl-CoA for the binding site
acetoacetyl-CoA
-
-
Co2+
-
-
crotonyl-CoA
-
-
Cu2+
-
-
glutaconyl-CoA
-
-
oct-2-yn-4-enoyl-CoA
-
irreversible and most likely involved covalent modification of the apoenzyme
p-chloromercuribenzoate
-
-
Zn2+
-
-
additional information
-
no inhibition by glutaconyl-CoA
-