1.3.8.6: glutaryl-CoA dehydrogenase (ETF)

This is an abbreviated version!
For detailed information about glutaryl-CoA dehydrogenase (ETF), go to the full flat file.

Word Map on EC 1.3.8.6

1.3.8.6

glutaric

aciduria

3-hydroxyglutaric

striatal

dystonia

encephalopathic

ga1

macrocephaly

inborn

neurometabolic

crises

glutarylcarnitine

hydroxylysine

carnitine

crotonyl-coa

glutaconic

intercurrent

3-oh-ga

frontotemporal

neuroradiological

acylcarnitine

excretors

medicine

glutaconyl-coa

acidaemia

subdural

isovaleryl-coa

glutarylation

sylvian

pharmacology

Reaction

Synonyms

decarboxylating glutaryl-coenzyme A dehydrogenase, EC 1.3.99.7, GCD, GCDH, GDH, GDHGeo, glutaryl coenzyme A dehydrogenase, glutaryl-CoA dehydrogenase, glutaryl-coenzyme A dehydrogenase, More

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.8 With a flavin as acceptor

1.3.8.6 glutaryl-CoA dehydrogenase (ETF)

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Results	in table
1	Activating Compound
1542	AA Sequence
9	Application
1	CAS Registry Number
8	Cloned(Commentary)
26	Cofactor
4	Crystallization (Commentary)
349	Disease/ Diagnostics
21	General Information
15	Inhibitors
5	kcat/KM [mM/s]
3	Ki Value [mM]
44	KM Value [mM]
15	Localization
12	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
253	Organism
9	Pathway
11	pH Optimum
1	pH Range
1	pH Stability
39	Protein Variants
16	Purification (Commentary)
5	Reaction
6	Reaction Type
51	Reference
49	Source Tissue
17	Specific Activity [micromol/min/mg]
1	Storage Stability
90	Substrates and Products (Substrate)
9	Subunits
39	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
6	Temperature Stability [°C]
30	Turnover Number [1/s]

Natural Substrates Products

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of the Enzyme Summary Page.

Natural Substrates Products on EC 1.3.8.6 - glutaryl-CoA dehydrogenase (ETF)

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glutaryl-CoA + acceptor

crotonoyl-CoA + CO2 + reduced acceptor

Homo sapiens

part of the degradative pathway of the amino acids tryptophan, lysine, and hydroxylysine, enzyme deficiency leads to glutaric aciduria type I leading to nonspecific developmental delay, hypotonia, and macrocephaly with cerebral atrophyof prenatal onset

656440

glutaryl-CoA + acceptor

crotonyl-CoA + CO2 + reduced acceptor

5 entries

glutaryl-CoA + electron transfer flavoprotein

(E)-but-2-enoyl-CoA + CO2 + reduced electron transfer flavoprotein

3 entries

glutaryl-CoA + electron transfer flavoprotein

crotonoyl-CoA + CO2 + reduced electron transfer flavoprotein

Homo sapiens

656812

glutaryl-CoA + electron transfer protein

crotonoyl-CoA + CO2 + reduced electron transfer protein

Homo sapiens

Q92947

654767

glutaryl-CoA + electron-transfer flavoprotein

crotonyl-CoA + CO2 + reduced electron-transfer flavoprotein

Homo sapiens

Q92947

overall reaction

762752

glutaryl-CoA + FAD

(E)-but-2-enoyl-CoA + CO2 + FADH2

3 entries

glutaryl-CoA + FAD

crotonoyl-CoA + CO2 + FADH2

3 entries

additional information

3 entries