1.3.98.1: dihydroorotate dehydrogenase (fumarate)
This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (fumarate), go to the full flat file.
Word Map on EC 1.3.98.1
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1.3.98.1
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pyrimidine
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leflunomide
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brequinar
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uridine
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plasmodium
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falciparum
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ubiquinone
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teriflunomide
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dhods
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1.3.3.1
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ump
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dihydro-orotate
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triazolopyrimidine
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atovaquone
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1.3.99.11
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dysostosis
-
analysis
-
medicine
-
acrofacial
- 1.3.98.1
- pyrimidine
- leflunomide
- brequinar
- uridine
- plasmodium
- falciparum
- ubiquinone
- teriflunomide
-
dhods
-
1.3.3.1
- ump
-
dihydro-orotate
- triazolopyrimidine
- atovaquone
-
1.3.99.11
- dysostosis
- analysis
- medicine
-
acrofacial
Reaction
Synonyms
(DHO) dehydrogenase, 4,5-L-dihydroorotate:oxygen oxidoreductase, ACT/DHOD, class 1A DHOD, class 1A DHODH, class 1A dihydroorotate dehydrogenase, DHOD, DHOD1, DHOD2, DHOD3, DHODA, DHOdehase, DHODH, DHODH-1A, dihydroorotate dehydrogenase, dihydroorotate dehydrogenase class 1A, Dihydroorotate oxidase, EC 1.3.3.1, LmDHODH, More, oxidase, dihydroorotate, TcDHOD
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Natural Substrates Products
Natural Substrates Products on EC 1.3.98.1 - dihydroorotate dehydrogenase (fumarate)
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REACTION DIAGRAM
orotate + reduced acceptor
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fourth step in synthesis of pyrimidine nucleotides
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?
(S)-dihydroorotate + acceptor
orotate + reduced acceptor
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fourth step in UMP-biosynthesis
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?
(S)-dihydroorotate + acceptor
orotate + reduced acceptor
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fourth step in synthesis of pyrimidine nucleotides
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?
(S)-dihydroorotate + fumarate
orotate + succinate
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enzyme is responsible for biosynthesis of succinate and orotate
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-
?
orotate + H2O2
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pathway of pyrimidine biosynthesis, constitutive biosynthetic enzyme
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?
(S)-dihydroorotate + O2
orotate + H2O2
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pathway of pyrimidine biosynthesis, constitutive biosynthetic enzyme
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?
L-dihydroorotate + fumarate
orotate + succinate
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DHODH catalyzes a coupled redox reaction in which dihydroorotate is oxidized to orotate and fumarate is reduced to succinate
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?