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1.3.99.18: quinaldate 4-oxidoreductase

This is an abbreviated version!
For detailed information about quinaldate 4-oxidoreductase, go to the full flat file.

Reaction

Quinaldate
+
acceptor
+
H2O
=
Kynurenate
+
reduced acceptor

Synonyms

Oxidase, quinaldate 4-, Quinaldic acid 4-oxidoreductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.18 quinaldate 4-oxidoreductase

Systematic Name

Systematic Name on EC 1.3.99.18 - quinaldate 4-oxidoreductase

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SYSTEMATIC NAME
IUBMB Comments
quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)
The enzyme from Pseudomonas sp. AK2 also acts on quinoline-8-carboxylate, whereas that from Serratia marcescens 2CC-1 will oxidize nicotinate; quinaldate is a substrate for both of these enzymes. 2,4,6-Trinitrobenzene sulfonate, 1,4-benzoquinone, 1,2-naphthoquinone, nitroblue tetrazolium, thionine and menadione will serve as an electron acceptor for the former enzyme and ferricyanide for the latter; Meldola blue, iodonitrotetrazolium chloride, phenazine methosulfate, 2,6-dichlorophenolindophenol and cytochrome c will act as electron acceptors for both.