1.3.99.8: 2-furoyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about 2-furoyl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

2-furoyl coenzyme A dehydrogenase, 2-furoyl coenzyme A hydroxylase, dehydrogenase, 2-furoyl coenzyme A, furoyl-CoA hydroxylase

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.99 With unknown physiological acceptors

                1.3.99.8 2-furoyl-CoA dehydrogenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
87	AA Sequence
1	CAS Registry Number
3	Cofactor
6	Inhibitors
4	KM Value [mM]
4	Metals/Ions
6	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
18	Organism
5	Pathway
2	pH Optimum
3	Purification (Commentary)
3	Reaction
3	Reaction Type
10	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
18	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 1.3.99.8 - 2-furoyl-CoA dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)

A copper protein. The oxygen atom of the -OH produced is derived from water, not O2; the actual oxidative step is probably dehydrogenation of a hydrated form -CHOH-CH2- to -C(OH)=CH-, which tautomerizes non-enzymically to -CO-CH2-, giving (5-oxo-4,5-dihydro-2-furoyl)-CoA. Methylene blue, nitro blue, tetrazolium and a membrane fraction from Pseudomonas putida can act as acceptors.