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1.3.99.B12: menaquinone-7 reductase (acceptor)

This is an abbreviated version!
For detailed information about menaquinone-7 reductase (acceptor), go to the full flat file.

Reaction

menaquinone-7 with partially saturated prenyl side chain
+
acceptor
=
menaquinone-7
+
reduced acceptor

Synonyms

AF0648, menaquinone-specific prenyl reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.B12 menaquinone-7 reductase (acceptor)

Substrates Products

Substrates Products on EC 1.3.99.B12 - menaquinone-7 reductase (acceptor)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
menaquinone-7 + reduced acceptor
?
show the reaction diagram
the enzyme is involved in the biosynthesis of menaquinone-7(14H) i.e. menaquinone with a fully saturated heptaprenyl side chain
-
-
?
menaquinone-7 + reduced dithionite
menaquinone-7 with partially saturated prenyl side chain + dithionite
show the reaction diagram
menaquinone-7 i.e. menaquinone with a fully saturated heptaprenyl side chain. The enzyme specifically reduces the prenyl side chain of menaquinone, whereas the prenyl moieties of ubiquinone-8 and geranygeranyl diphosphates are relatively resistant to reduction. The enzyme is not able to utilize NAD(P)H as the electron donor
-
-
?