1.4.1.14: glutamate synthase (NADH)
This is an abbreviated version!
For detailed information about glutamate synthase (NADH), go to the full flat file.
Word Map on EC 1.4.1.14
Reaction
2 L-glutamate
+
Synonyms
gltA, GltA2, gltB, glutamate (reduced nicotinamide adenine dinucleotide) synthase, glutamate synthase, glutamate synthase (NADH), glutamate synthase (NADH-dependent), glutamate synthetase, glutamine 2-oxoglutarate aminotransferase, GOGAT, GOGAT1, GOGAT2, L-glutamate synthase (NADH), L-glutamate synthetase, NADH glutamate synthase, NADH-dependent glutamate synthase, NADH-dependent glutamine-2-oxoglutarate aminotransferase, NADH-GltS, NADH-glutamate synthase, NADH-GOGAT, NADH-GOGAT I, NADH-GOGAT II, NADH-GOGAT1, NADH-GOGAT2, NADH: GOGAT, Os01g0681900, Os05g0555600, synthase, glutamate (reduced nicotinamide adenine dinucleotide)
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1.4.1.14 glutamate synthase (NADH)Advanced search results
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Activating Compound on EC 1.4.1.14 - glutamate synthase (NADH)
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ACTIVATING COMPOUND 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
2-mercaptoethanol
-
1%, presence of a reducing agent is essential for enzyme activity
diphosphate
-
5 mM, stimulates activity with 36% enhancement
dithiothreitol
-
0.5 mg per ml, presence of a reducing agent is essential for enzyme activity
GltB
-
GltA and not GltA2 is dependent on GltB for GOGAT activity in vivo
-
NH4Cl
-
NADH-GOGAT gene expression is transiently induced within a few hours of supplying either 1 or 25 mM to the medium, leading to a marked accumulation of NADH-GOGAT mRNA
NH4NO3
-
transcripts for NADH-GOGAT transiently accumulate when 0.5 mM is applied
succinate
-
50 mM, stimulates activity by 57%
additional information
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not activated by pyridoxal 5-phosphate and pyridoxamine 5-phosphate
-
additional information
-
supply of NH4+ at low concentrations increases the expression of the enzyme: supply with 1 mM NH4+ for 24 h increases the enzyme content in the epidermis and exodermis of the root surface
-
additional information
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supply of NH4+ at low concentrations increases the expression of the enzyme: supply with 1 mM NH4+ for 24 h increases the enzyme content in the epidermis and exodermis of the root surface
-
additional information
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NH4+ transiently induces accumulation of enzyme mRNA in roots of rice seedlings, maximally 3-6 h after supply
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