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1.4.1.16: diaminopimelate dehydrogenase

This is an abbreviated version!
For detailed information about diaminopimelate dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.16

Reaction

meso-2,6-diaminoheptanedioate
+
H2O
+
NADP+
=
L-2-amino-6-oxoheptanedioate
+
NH3
+
NADPH
+
H+

Synonyms

BAB07799, BF3690, DAPDH, DDH, meso-2,6-diaminopimelate dehydrogenase, meso-alpha,epsilon-diaminopimelate dehydrogenase, meso-DAPDH, meso-diaminopimelate dehydrogenase, NADP+-dependent meso-diaminopimelate dehydrogenase, Sth1425, Theth_1310

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.16 diaminopimelate dehydrogenase

Turnover Number

Turnover Number on EC 1.4.1.16 - diaminopimelate dehydrogenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.17
2-oxo-3-methylbutanoate
mutant W121L/H227I, pH 9, 30°C
6.2
2-oxo-3-phenylpropanoate
mutant W121L/H227I, pH 9, 30°C
13.49
2-oxo-4-methylpentanoate
mutant W121L/H227I, pH 9, 30°C
12.6
2-oxo-4-phenylbutanoate
mutant W121L/H227I, pH 9, 30°C
35.38
2-oxobutanoate
mutant W121L/H227I, pH 9, 30°C
38.7
2-oxopentanoate
mutant W121L/H227I, pH 9, 30°C
0.91 - 0.93
2-oxovalerate
0.27 - 0.38
3-methyl-2-oxobutanoate
0.1 - 0.12
4-methyl-2-oxopentanoate
4.9 - 278.2
L-DELTA1-tetrahydrodipicolinate
-
1.58 - 127000
meso-2,6-diaminoheptanedioate
775 - 8933
NAD+
5.97
NADH
pH 8.2, 37°C
17.91 - 830
NADP+
0.73 - 6.97
NADPH
160.8 - 1815.6
NH4+
0.087 - 0.11
oxaloacetate
0.11 - 3.98
phenylpyruvate
1.35 - 10100
pyruvate