1.4.1.19: tryptophan dehydrogenase

This is an abbreviated version!
For detailed information about tryptophan dehydrogenase, go to the full flat file.

Reaction

Synonyms

dehydrogenase, tryptophan, L-Trp dehydrogenase, L-Trp-dehydrogenase, L-tryptophan dehydrogenase, NAD(P)-L-tryptophan dehydrogenase, NAD+-dependent L-tryptophan dehydrogenase, TDH, TrpDH

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.1 With NAD⁺ or NADP⁺ as acceptor

1.4.1.19 tryptophan dehydrogenase

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Results	in table
1	Activating Compound
23	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
23	Cofactor
1	Crystallization (Commentary)
3	Inhibitors
19	kcat/KM [mM/s]
1	Ki Value [mM]
28	KM Value [mM]
3	Localization
5	Metals/Ions
1	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
18	Organism
6	PDB ID
3	pH Optimum
1	pH Stability
29	Protein Variants
3	Purification (Commentary)
1	Reaction
5	Reaction Type
18	Reference
14	Source Tissue
22	Specific Activity [micromol/min/mg]
31	Substrates and Products (Substrate)
6	Subunits
17	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
19	Turnover Number [1/s]

Reference

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Reference on EC 1.4.1.19 - tryptophan dehydrogenase

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391536

El Bahr, M.K.; Kutacek, M.; Opatrny, Z.

L-tryptophan aminotransferase and L-tryptophan dehydrogenase, enzymes of IAA synthesis, in normal and tumorous tobacco tissue cultures

Biochem. Physiol. Pflanz.

182

213-222

1987

Nicotiana tabacum

391537

Kutacek, M.

Auxin biosynthesis and its regulation on the molecular level

Biol. Plant.

145-153

1985

Solanum lycopersicum, no activity in Brassica oleracea, Pisum sativum, Zea mays

391538

Vackova, K.; Mehta, A.; Kutacek, M.

Tryptophan aminotransferase and tryptophan dehydrogenase activities in some cell compartments of spinach leaves: the effect of calcium ions on tryptophan dehydrogenase

Biol. Plant.

154-158

1985

Spinacia oleracea

391539

Ebeid, M.M.; Dimova, S.; Kutacek, M.

Substrate specificity of L-tryptophan dehydrogenase and its distribution in plants

Biol. Plant.

413-416

1985

Solanum lycopersicum, no activity in Brassica oleracea, Pisum sativum, Prosopis juliflora, Zea mays

391540

Tan Hoang Minh, M.; Kutacek, M.; Sebanek, J.

Growth-correlative effect of the root on the apical part of the epicotyl in pea seedlings regarding the IAA content and L-tryptophan aminotransferase and L-tryptophan dehydrogenase activities

Biol. Plant.

342-348

1984

Pisum sativum

741706

Wakamatsu, T.; Sakuraba, H.; Kitamura, M.; Hakumai, Y.; Fukui, K.; Ohnishi, K.; Ashiuchi, M.; Ohshima, T.

Structural insights into l-tryptophan dehydrogenase from a photoautotrophic Cyanobacterium, Nostoc punctiforme

Appl. Environ. Microbiol.

e02710

2017

Nostoc punctiforme (W8CV45), Nostoc punctiforme, Nostoc punctiforme NIES-2108 (W8CV45), Nostoc punctiforme NIES-2108

27815281

742410

Ogura, R.; Wakamatsu, T.; Mutaguchi, Y.; Doi, K.; Ohshima, T.

Biochemical characterization of an L-tryptophan dehydrogenase from the photoautotrophic cyanobacterium Nostoc punctiforme

Enzyme Microb. Technol.

40-46

2014

Nostoc punctiforme, Nostoc punctiforme NIES-2108

24835098

742947

Matsui, D.; Okazaki, S.; Matsuda, M.; Asano, Y.

Enhancement of stability of L-tryptophan dehydrogenase from Nostoc punctiforme ATCC29133 and its application to L-tryptophan assay

J. Biotechnol.

196-197

27-32

2015

Nostoc punctiforme (W8CV45), Nostoc punctiforme ATCC29133 (W8CV45), Nostoc punctiforme ATCC29133

25615944