1.4.3.1: D-aspartate oxidase

This is an abbreviated version!
For detailed information about D-aspartate oxidase, go to the full flat file.

Word Map on EC 1.4.3.1

1.4.3.1

d-amino

n-methyl-d-aspartate

nmda

d-serine

d-glutamate

octopus

nmdar-dependent

d-alanine

prepulse

humicola

d-amino-acid

d-ser

d-glu

drug development

molecular biology

medicine

Reaction

Synonyms

aspartic oxidase, C47A10.5 gene product, C47Ap, ChDASPO, ChDDO, D-Asp oxidase, D-aspartic oxidase, D-AspO, DAO, DASOX, DASPO, DDO, DDO-1, DDO-2, DDO-3, DDO1, DDO3, F18E3.7a gene product, F18Ep

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.3 With oxygen as acceptor

1.4.3.1 D-aspartate oxidase

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Results	in table
2	Activating Compound
342	AA Sequence
4	Application
1	CAS Registry Number
32	Cloned(Commentary)
61	Cofactor
2	Crystallization (Commentary)
3	Disease/ Diagnostics
2	Expression
16	General Information
1	General Stability
38	IC50 Value
133	Inhibitors
51	kcat/KM [mM/s]
21	Ki Value [mM]
153	KM Value [mM]
42	Localization
1	Metals/Ions
30	Molecular Weight [Da]
114	Natural Substrates/ Products (Substrates)
294	Organism
5	Pathway
6	PDB ID
14	pH Optimum
6	pH Range
5	pH Stability
35	Protein Variants
27	Purification (Commentary)
1	Reaction
3	Reaction Type
117	Reference
191	Source Tissue
68	Specific Activity [micromol/min/mg]
1	Storage Stability
338	Substrates and Products (Substrate)
25	Subunits
89	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
8	Temperature Stability [°C]
70	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 1.4.3.1 - D-aspartate oxidase

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30 - 60

Homo sapiens

Q99489

after 30 min of incubation, there is no loss of activity until the preincubation temperature reaches 45°C, and 9% of the maximum activity is lost at 50°C. The enzyme retains half of its maximum activity at 55°C, while almost all of the activity is lost at 60°C

742035

Vanrija humicola

Q75WF1

little loss of activity

48.8

melting temperature

T50 value

52.5

melting temperature, presence of FAD

763008

Vanrija humicola

Q75WF1

complete loss of activity

655928