1.4.3.3: D-amino-acid oxidase
This is an abbreviated version!
For detailed information about D-amino-acid oxidase, go to the full flat file.
Word Map on EC 1.4.3.3
-
1.4.3.3
-
d-serine
-
schizophrenia
-
peroxisomal
-
flavin
-
n-methyl-d-aspartate
-
d-alanine
-
catalase
-
fad
-
nmda
-
deamination
-
benzoate
-
flavoenzyme
-
flavoproteins
-
racemase
-
variabilis
-
l-amino
-
neurotransmission
-
d-aspartate
-
gracilis
-
co-agonist
-
rhodotorula
-
cephalosporin
-
glutamatergic
-
urate
-
d-proline
-
d-ala
-
d-ser
-
imino
-
antipsychotic
-
hypofunction
-
d-methionine
-
isoalloxazine
-
acylase
-
fad-containing
-
toruloides
-
rhodosporidium
-
d-glutamate
-
fad-dependent
-
d-cysteine
-
kynurenic
-
sulfurtransferase
-
d-valine
-
synthesis
-
medicine
-
d-leucine
-
cerium
-
7-aminocephalosporanic
-
d-tryptophan
-
d-phenylalanine
-
neuregulin
-
3-mercaptopyruvate
-
sarcosine
-
industry
-
biotechnology
-
analysis
-
diagnostics
-
drug development
-
pharmacology
- 1.4.3.3
- d-serine
-
schizophrenia
- peroxisomal
- flavin
- n-methyl-d-aspartate
- d-alanine
- catalase
- fad
- nmda
-
deamination
- benzoate
-
flavoenzyme
- flavoproteins
- racemase
- variabilis
-
l-amino
-
neurotransmission
- d-aspartate
- gracilis
-
co-agonist
- rhodotorula
- cephalosporin
-
glutamatergic
- urate
- d-proline
- d-ala
- d-ser
-
imino
-
antipsychotic
-
hypofunction
- d-methionine
- isoalloxazine
- acylase
-
fad-containing
- toruloides
- rhodosporidium
- d-glutamate
-
fad-dependent
- d-cysteine
-
kynurenic
- sulfurtransferase
- d-valine
- synthesis
- medicine
- d-leucine
- cerium
-
7-aminocephalosporanic
- d-tryptophan
- d-phenylalanine
- neuregulin
- 3-mercaptopyruvate
- sarcosine
- industry
- biotechnology
- analysis
- diagnostics
- drug development
- pharmacology
Reaction
Synonyms
chDAO, D-AAO, D-amino acid oxidase, D-amino-acid-oxidase, D-aminoacid oxidase, DAAO, DAMOX, DAO, DAO1, DaoE, hDAAO, ophio-amino-acid oxidase, oxidase, D-amino acid, PEG-DAO, pkDAAO, RgDAAO, TvDAAO, TvDAO, LH99
ECTree
1.4.3.3 D-amino-acid oxidaseAdvanced search results
results (
results (IC50 Value
IC50 Value on EC 1.4.3.3 - D-amino-acid oxidase
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IC50 VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0088
([4-[(3,4-dichloro-5-methyl-1H-pyrrole-2-carbonyl)amino]-1H-pyrrole-2-carbonyl]amino)acetic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
-
0.00039
([4-[(4,5-dibromo-1H-pyrrole-2-carbonyl)amino]-1H-pyrrole-2-carbonyl]amino)acetic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
-
0.0052
([4-[(4,5-dichloro-1H-pyrrole-2-carbonyl)amino]-1H-pyrrole-2-carbonyl]amino)acetic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
-
0.0067
([4-[(4-bromo-1H-pyrrole-2-carbonyl)amino]-1H-pyrrole-2-carbonyl]amino)acetic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
-
0.005
1,4-dihydropyrrolo[3,2-c]pyrazole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.005
2,3-dimethyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
1
2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylic acid
Sus scrofa
-
at pH 8.2 and 37°C
0.005
2-(2,4-dichlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.04
2-(3,3-dimethylbutyl)-6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.005
2-(3-chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.005
2-(4-chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.005
2-chloro-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.005
2-chloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.005
2-phenyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.0005
2-[(3,4-dichlorophenoxy)methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0007
2-[(4-chlorophenoxy)methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0008
2-[(4-fluorophenoxy)methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.02
2-[(benzyloxy)methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.00044
2-[2-(1H-benzimidazol-1-yl)ethyl]-6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00036
2-[[(1Z)-1-chloroprop-1-en-1-yl]sulfanyl]prop-2-enoic acid
Homo sapiens
pH 8.5, 23°C
-
0.0001
2-[[(3,4-dichlorophenyl)sulfanyl]methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0002
2-[[(4-chlorophenyl)sulfanyl]methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0003
2-[[(4-fluorophenyl)sulfanyl]methyl]-5-hydroxy-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.005
3-(3-chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.005
3-(4-chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.0001
3-(benzylsulfanyl)-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.005
3-(hydroxymethyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.00007
3-benzyl-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.000128
3-hydroxy-1,5-naphthyridin-2(1H)-one hydrobromide
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000784
3-hydroxy-1,7-naphthyridin-2(1H)-one hydrobromide
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0173
3-hydroxy-4-methylquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0000039
3-hydroxy-5-(2-phenylethyl)pyridin-2(1H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.00014
3-hydroxy-5-methylpyridin-2(1H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.00275
3-hydroxy-6-methylquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000197
3-hydroxy-7-methylquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000038
3-hydroxy-8-methylquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0015
3-hydroxypyridin-2(1H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000004
3-hydroxyquinolin-2-(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.005
3-pyridin-3-yl-4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.0006
3-[(cyclohexylmethyl)sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.0002
3-[[(1,2-benzoxazol-3-yl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.00006
3-[[(2H-1,3-benzodioxol-5-yl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.00005
3-[[(3,4-dichlorophenyl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.00003
3-[[(4-chlorophenyl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.0003
3-[[(4-tert-butylphenyl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.00003
3-[[(6-fluoronaphthalen-2-yl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.0007
3-[[([1,1'-biphenyl]-3-yl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.00009
3-[[([1,1'-biphenyl]-4-yl)methyl]sulfanyl]-5-hydroxy-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.0000049
4-hydroxy-6-(1-phenylethyl)pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000038
4-hydroxy-6-(2-phenylethyl)pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000013
4-hydroxy-6-(3-phenylpropyl)pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000022
4-hydroxy-6-(phenoxymethyl)pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000021
4-hydroxy-6-[2-(3-methoxyphenyl)ethyl]pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000029
4-hydroxy-6-[2-(4-methoxyphenyl)ethyl]pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000112
4-hydroxy-6-[2-(7-hydroxy-2-oxo-4-phenyl-2H-1-benzopyran-6-yl)ethyl]pyridazin-3(2H)-one
Homo sapiens
pH 8, 37°C
-
0.0000084
4-hydroxy-6-[2-[2-(trifluoromethyl)phenyl]ethyl]pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000024
4-hydroxy-6-[2-[3-(trifluoromethyl)phenyl]ethyl]pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000012
4-hydroxy-6-[2-[4-(trifluoromethyl)phenyl]ethyl]pyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000073
4-hydroxy-6-[2-[7-hydroxy-4-(3-methoxyphenyl)-2-oxo-2H-1-benzopyran-6-yl]ethyl]pyridazin-3(2H)-one
Homo sapiens
pH 8, 37°C
-
0.000052
4-hydroxy-6-[2-[7-hydroxy-4-(3-methylphenyl)-2-oxo-2H-1-benzopyran-6-yl]ethyl]pyridazin-3(2H)-one
Homo sapiens
pH 8, 37°C
-
0.000474
4-hydroxy-6-[2-[7-hydroxy-4-(4-methylphenyl)-2-oxo-2H-1-benzopyran-6-yl]ethyl]pyridazin-3(2H)-one
Homo sapiens
pH 8, 37°C
-
0.005
4H-pyrrolo[2,3-d][1,3]oxazole-5-carboxylic acid
Homo sapiens
IC50 above 0.005 mM
0.000047
5-chloro-3-hydroxypyridin-2(1H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0005
5-hydroxy-2-(2-phenylethyl)-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.05
5-hydroxy-2-(methoxymethyl)-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0009
5-hydroxy-2-(phenoxymethyl)-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0009
5-hydroxy-2-[(naphthalen-1-yloxy)methyl]-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0008
5-hydroxy-2-[(naphthalen-2-yloxy)methyl]-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.0002
5-hydroxy-2-[(phenylsulfanyl)methyl]-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.003
5-hydroxy-2-[(pyridin-3-yloxy)methyl]-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.004
5-hydroxy-2-[(pyrimidin-2-ylsulfanyl)methyl]-4H-pyran-4-one
Homo sapiens
pH and temperature not specified in the publication
0.00006
5-hydroxy-3-(2-phenylethyl)-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.004
5-hydroxy-3-(3-phenylpropyl)-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.04
5-hydroxy-3-[(2-phenylethyl)sulfanyl]-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.00005
5-hydroxy-3-[[(4-iodophenyl)methyl]sulfanyl]-1,2,4-triazin-6(1H)-one
Homo sapiens
-
pH and temperature not specified in the publication
0.0000047
6-(2-cyclohexylethyl)-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.00067
6-(3,3-dimethylbutyl)-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.3
6-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.000155
6-chloro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0003
6-cyclohexyl-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0001
6-hydroxy-2-(2-(naphthalen-1-yl)ethyl)-1,2,4-triazine-3,5-(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00007
6-hydroxy-2-(2-phenylethyl)-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00026
6-hydroxy-2-(3-methylbutyl)-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.0017
6-hydroxy-2-(3-phenylpropyl)-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00005
6-hydroxy-2-[(naphthalen-1-yl)methyl]-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00022
6-hydroxy-2-[(naphthalen-2-yl)methyl]-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00033
6-hydroxy-2-[2-(1H-pyrazol-1-yl)ethyl]-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00031
6-hydroxy-2-[2-(1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl]-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00076
6-hydroxy-2-[2-(pyridin-2-yl)ethyl]-1,2,4-triazine-3,5(2H,4H)-dione
Homo sapiens
-
at pH 8.5 and 25°C
0.00012
6-[(E)-2-(4-chlorophenyl)vinyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000002
6-[2-(2-fluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000015
6-[2-(3,5-difluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000013
6-[2-(3,5-dimethoxyphenyl)ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000014
6-[2-(3-fluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000027
6-[2-(4-chlorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.0000031
6-[2-(4-fluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000063
6-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000069
6-[2-[4-(3-chlorophenyl)-7-hydroxy-2-oxo-2H-1-benzopyran-6-yl]ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
pH 8, 37°C
-
0.000119
6-[2-[4-(4-chlorophenyl)-7-hydroxy-2-oxo-2H-1-benzopyran-6-yl]ethyl]-4-hydroxypyridazin-3(2H)-one
Homo sapiens
pH 8, 37°C
-
0.00053
7,8-dibromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.00065
7,8-dichloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.00048
7-bromo-8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.0004
7-bromo-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.0001
7-chloro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0226
7-ethyl-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.05
7-hydroxypyrido[2,3-b]pyrazin-6(5H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0229
7-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.3
8-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.0144
8-ethyl-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.3
8-phenylethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.3
8-phenylpropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.00052
8-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
1
methyl 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate
Sus scrofa
-
at pH 8.2 and 37°C
0.00049
[[4-[(4,5-dibromo-1H-pyrrole-2-carbonyl)amino]-1H-pyrrole-2-carbonyl](methyl)amino]acetic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
-
0.000032
3-hydroxy-1,6-naphthyridin-2(1H)-one hydrobromide
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.003081
3-hydroxy-1,6-naphthyridin-2(1H)-one hydrobromide
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000008
3-hydroxy-1,8-naphthyridin-2(1H)-one hydrobromide
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000009
3-hydroxy-1,8-naphthyridin-2(1H)-one hydrobromide
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0002
3-hydroxy-1,8-naphthyridin-2(1H)-one hydrobromide
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000424
3-hydroxy-1,8-naphthyridin-2(1H)-one hydrobromide
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000016
3-hydroxy-5-methylquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.00847
3-hydroxy-5-methylquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000004
3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.0000069
3-hydroxyquinolin-2(1H)-one
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000215
3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.0000014
4H-furo[3,2-b]pyrrole-5-carboxylic acid
Homo sapiens
-
in 50 mM potassium phosphate buffer (pH 7.5), at 22°C
0.000004
5-chloro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.00004
5-chloro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000003
5-chloro-6-fluoro-3-hydroxy-1,8-naphthyridin-2(1H)-one hydrobromide
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000004
5-chloro-6-fluoro-3-hydroxy-1,8-naphthyridin-2(1H)-one hydrobromide
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000005
5-chloro-6-fluoro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.00005
5-chloro-6-fluoro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000008
5-ethyl-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.003665
5-ethyl-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000008
5-fluoro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000196
5-fluoro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.00091
5-methylpyrazole-3-carboxylic acid
Homo sapiens
-
pH and temperature not specified in the publication
0.00019
6-chlorobenzo[d]isoxazol-3-ol
Homo sapiens
-
pH and temperature not specified in the publication
0.000009
6-fluoro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.000308
6-fluoro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.00026
7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.00113
7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Homo sapiens
-
at pH 8.2 and 37°C
0.00416
7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Rattus norvegicus
-
at pH 8.2 and 37°C
0.00001
7-fluoro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.001445
7-fluoro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.00015
7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Rattus norvegicus
-
at pH 8.2 and 37°C
0.00015
7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.00034
7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Homo sapiens
-
at pH 8.2 and 37°C
0.00023
8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Homo sapiens
-
at pH 8.2 and 37°C
0.00224
8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Rattus norvegicus
-
at pH 8.2 and 37°C
0.00024
8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Sus scrofa
-
at pH 8.2 and 37°C
0.00138
8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Homo sapiens
-
at pH 8.2 and 37°C
0.00799
8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Rattus norvegicus
-
at pH 8.2 and 37°C
0.00014
8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Rattus norvegicus
-
at pH 8.2 and 37°C
0.00021
8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Homo sapiens
-
at pH 8.2 and 37°C
0.000033
8-chloro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.00872
8-chloro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
0.000003
8-fluoro-3-hydroxyquinolin-2(1H)-one
Homo sapiens
pH 8.5, recombinant enzyme, with substrate D-serine
0.00018
8-fluoro-3-hydroxyquinolin-2(1H)-one
Rattus norvegicus
-
pH 8.5, recombinant enzyme, with substrate D-serine
additional information
additional information
Homo sapiens
IC50 with substrate D-aspartate, overview
-
additional information
additional information
Homo sapiens
-
IC50 with substrate D-aspartate, overview
-
