1.4.3.3: D-amino-acid oxidase
This is an abbreviated version!
For detailed information about D-amino-acid oxidase, go to the full flat file.
Word Map on EC 1.4.3.3
-
1.4.3.3
-
d-serine
-
schizophrenia
-
peroxisomal
-
flavin
-
n-methyl-d-aspartate
-
d-alanine
-
catalase
-
fad
-
nmda
-
deamination
-
benzoate
-
flavoenzyme
-
flavoproteins
-
racemase
-
variabilis
-
l-amino
-
neurotransmission
-
d-aspartate
-
gracilis
-
co-agonist
-
rhodotorula
-
cephalosporin
-
glutamatergic
-
urate
-
d-proline
-
d-ala
-
d-ser
-
imino
-
antipsychotic
-
hypofunction
-
d-methionine
-
isoalloxazine
-
acylase
-
fad-containing
-
toruloides
-
rhodosporidium
-
d-glutamate
-
fad-dependent
-
d-cysteine
-
kynurenic
-
sulfurtransferase
-
d-valine
-
synthesis
-
medicine
-
d-leucine
-
cerium
-
7-aminocephalosporanic
-
d-tryptophan
-
d-phenylalanine
-
neuregulin
-
3-mercaptopyruvate
-
sarcosine
-
industry
-
biotechnology
-
analysis
-
diagnostics
-
drug development
-
pharmacology
- 1.4.3.3
- d-serine
-
schizophrenia
- peroxisomal
- flavin
- n-methyl-d-aspartate
- d-alanine
- catalase
- fad
- nmda
-
deamination
- benzoate
-
flavoenzyme
- flavoproteins
- racemase
- variabilis
-
l-amino
-
neurotransmission
- d-aspartate
- gracilis
-
co-agonist
- rhodotorula
- cephalosporin
-
glutamatergic
- urate
- d-proline
- d-ala
- d-ser
-
imino
-
antipsychotic
-
hypofunction
- d-methionine
- isoalloxazine
- acylase
-
fad-containing
- toruloides
- rhodosporidium
- d-glutamate
-
fad-dependent
- d-cysteine
-
kynurenic
- sulfurtransferase
- d-valine
- synthesis
- medicine
- d-leucine
- cerium
-
7-aminocephalosporanic
- d-tryptophan
- d-phenylalanine
- neuregulin
- 3-mercaptopyruvate
- sarcosine
- industry
- biotechnology
- analysis
- diagnostics
- drug development
- pharmacology
Reaction
Synonyms
chDAO, D-AAO, D-amino acid oxidase, D-amino-acid-oxidase, D-aminoacid oxidase, DAAO, DAMOX, DAO, DAO1, DaoE, hDAAO, ophio-amino-acid oxidase, oxidase, D-amino acid, PEG-DAO, pkDAAO, RgDAAO, TvDAAO, TvDAO, LH99
ECTree
1.4.3.3 D-amino-acid oxidaseAdvanced search results
results (
results (Turnover Number
Turnover Number on EC 1.4.3.3 - D-amino-acid oxidase
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TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
4.33
(RS)-1-(4-chlorophenyl)-1-phenylmethanamine
mutant I230F/R283G, 30°C, pH 8.0
-
5.48
(RS)-1-(4-chlorophenyl)-1-phenylmethanamine
mutant I230C/R283G, 30°C, pH 8.0
-
6.01
(RS)-1-(4-chlorophenyl)-1-phenylmethanamine
mutant I230A/R283G, 30°C, pH 8.0
-
1.3
cephalosporin C
mutant enzyme Y223S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
3 - 6
cephalosporin C
-
immobilized enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
3.6
cephalosporin C
mutant enzyme M213R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
4.4
cephalosporin C
mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
6.167
cephalosporin C
recombinant wild-type enzyme, pH 7.5, 22°C
7
cephalosporin C
mutant enzyme S335R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
7.3
cephalosporin C
mutant enzyme M213E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
7.8
cephalosporin C
mutant enzyme Y228F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
15
cephalosporin C
mutant enzyme Y238S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
17
cephalosporin C
mutant enzyme Y223F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
24
cephalosporin C
mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
24
cephalosporin C
mutant enzyme Y238R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
26
cephalosporin C
mutant enzyme S335H, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
50
cephalosporin C
mutant enzyme S335G, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
55
cephalosporin C
-
free enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
57
cephalosporin C
-
immobilized enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
70
cephalosporin C
-
free enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
72
cephalosporin C
wild type enzyme, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
108.6
D-Ala
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
0.63
D-alanine
mutant enzyme Y223S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.79
D-alanine
mutant enzyme Q339N, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
3.7
D-alanine
mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
6.9
D-alanine
mutant enzyme M213E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
9.2
D-alanine
mutant enzyme S335R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
10
D-alanine
mutant enzyme M213R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
15
D-alanine
mutant enzyme Y238R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
23.3
D-alanine
-
immobilized enzyme, in 100 mM potassium phosphate buffer at pH 8.0 and 25°C
25
D-alanine
mutant enzyme Y228F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
25
D-alanine
mutant enzyme Y238S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
44
D-alanine
-
immobilized enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
48
D-alanine
mutant enzyme S335G, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
51
D-alanine
-
immobilized enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
52.4
D-alanine
-
free enzyme, in 100 mM potassium phosphate buffer at pH 8.0 and 25°C
60
D-alanine
-
free enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
67
D-alanine
mutant enzyme Y223F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
74
D-alanine
-
free enzyme, in 100 mM potassium phosphate buffer, pH 8.0, at 25°C
75
D-alanine
mutant enzyme S335H, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
81
D-alanine
wild type enzyme, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
95
D-alanine
apparent value, reconstituted holoenzyme at pH 8.0 and 30°C
370
D-alanine
pH 8.5, 15°C, mutant S19G/S120P/Q144R/K321M/A345V
0.2
D-arginine
kcat less than 0.2/s, mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.43
D-arginine
mutant enzyme Y223S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
2.1
D-arginine
mutant enzyme S335H, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
2.6
D-arginine
mutant enzyme Y238R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
3.2
D-arginine
mutant enzyme M213E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
3.6
D-arginine
mutant enzyme S335R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
6.5
D-arginine
mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
7.3
D-arginine
mutant enzyme Y223F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
8.6
D-arginine
mutant enzyme S335G, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
11
D-arginine
mutant enzyme Y228F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
14
D-arginine
mutant enzyme Y238S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
20
D-arginine
wild type enzyme, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.7
D-Asn
-
Km less than 0.7 s-1, mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
13
D-Asn
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
50
D-Asn
-
mutant enzyme F258Y, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
62.4
D-Asn
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
0.09
D-Aspartate
mutant enzyme S335H, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.26
D-Aspartate
mutant enzyme Y228F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.37
D-Aspartate
mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.5
D-Aspartate
mutant enzyme S335G, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.5
D-Aspartate
wild type enzyme, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.56
D-Aspartate
mutant enzyme Y238S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.67
D-Aspartate
mutant enzyme S335R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
0.9
D-Aspartate
mutant enzyme Y223S, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
1
D-Aspartate
mutant enzyme Q339E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
2.5
D-Aspartate
mutant enzyme Y223F, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
3.2
D-Aspartate
mutant enzyme M213E, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
3.9
D-Aspartate
mutant enzyme M213R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
6
D-Aspartate
mutant enzyme Y238R, in 50 mM sodium diphosphate, pH 8.5, at air (21%) oxygen saturation, at 25°C, apparent value
29.1
D-Leu
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
46
D-Leu
-
mutant enzyme F258Y, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
56
D-Leu
-
mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
66.6
D-Leu
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
3.54
D-Lys
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
42
D-Met
-
mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
63
D-Met
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
80.5
D-Met
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
89
D-Met
-
mutant enzyme F258Y, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
0.84
D-methionine
-
recombinant mutant C108S, pH 7.5, 37°C, with 6-dichloroindophenolate
1.5
D-methionine
-
recombinant wild-type enzyme, pH 7.5, 37°C, with 6-dichloroindophenolate
2.8
D-methionine
-
recombinant mutant C108D, pH 7.5, 37°C, with 6-dichloroindophenolate
200
D-methionine
-
recombinant wild-type enzyme, pH 7.5, 37°C, with O2
27.2
D-Phe
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
47.1
D-Phe
-
mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
58.8
D-Phe
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
63
D-Phe
-
mutant enzyme F258Y, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
15.5
D-phenylalanine
in 50 mM sodium diphosphate buffer (pH 8.3) at 25°C
20.5
D-Ser
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
1.75
D-Thr
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
7.7
D-Trp
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
31
D-Trp
-
mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
33
D-Trp
-
mutant enzyme F258Y, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
42.4
D-Trp
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
15.9
D-Tyr
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
22.5
D-Tyr
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
72
D-Tyr
-
mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
11.5
D-Val
-
mutant enzyme F258S, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
14.6
D-Val
-
mutant enzyme F258A, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
85.3
D-Val
-
wild type enzyme, in 50 mM potassium phosphate buffer, pH 8.0, at 30°C
