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1.4.3.4: monoamine oxidase

This is an abbreviated version!
For detailed information about monoamine oxidase, go to the full flat file.

Word Map on EC 1.4.3.4

Reaction

RCH2NHR'
+
H2O
 +
O2
=
RCHO
 +
R'NH2
 +
H2O2

Synonyms

adrenaline oxidase, amine-oxygen oxidoreductase, C-MAO, EC 1.4.3.9, epinephrine oxidase, MAO, MAO A, MAO B, MAO type B, MAO-A, MAO-B, MAO-N, MAO-N-D5, MAOA, MAOB, monoamine oxidase, monoamine oxidase A, monoamine oxidase B, monoamine oxidase N, monoamine oxidase type B, monoamine oxidase-A, monoamine oxidase-B, monoamine oxidaseA, monoamine oxidases A, monoamine oxidases B, monoamine-oxidase-A, monoamine: O2-oxidoreductase, deaminated, monoamine: O2-oxidoreductase, deaminating, monoamine: O2-oxidoreductase: deaminating, monoamine:O2 oxidoreductase (deaminating), monoamine:O2 oxidoreductase, deaminating, monoamine:O2-oxidoreductase deaminating, monoaminoxidase B, More, semicarbazide-sensitive amine oxidase, serotonin deaminase, SSAO, tyraminase, tyramine oxidase, zMAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.4 monoamine oxidase

Cloned

Cloned on EC 1.4.3.4 - monoamine oxidase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
advantage of the expression in Pichia pastoris compared with the expression in Saccharomyces cerevisiae: a higher level of homogeneity of the isolated enzyme
development of expression systems for human MAO-B and MAO-A, e.g. overexpression in the outer mitochondrial membranes of a Pichia pastoris or a Saccharomyces cerevisiae yeast system
-
DNA and amino acid sequence determination and analysis, phylogenetic analysis
-
expressed in COS-1 cells
expressed in Escherichia coli BL21-Gold (DE3), BL21 Plyse, and BL21 Plysee cells
-
expressed in Pichia pastoris
expressed in Pichia pastoris. Recombinant rMAOB, overexpressed in Pichia pastoris, is exclusively localized in the outer mitochondrial membrane of the Pichia cells
expression in a human embryonic kidney cell line and expression in mammalian cells
-
expression in Cos-1 cells
expression in Esherichia coli, two forms of the enzyme: a catalytically active form exhibits similar properties as rat liver enzyme and an inactive form
-
expression in Pichia pastoris
expression in Saccharomyces cerevisiae
expression in Saccharomyces cerevisiae BJ 2168
-
expression in Saccharomyces cerevisiae YSA-1C
-
expression in Sf21 insect cells
-
expression in yeast
-
expression of hMAO-A and hMAO-B in insect cells BTI-TN-5B1-4 using the baculovirus infection system
-
expression of MAO-A and MAO-B in baculovirus infected BTI insect cells
expression of MAO-A in Pichia pastoris mitochondria
expression of MAO-B in Pichia pastoris mitochondria, recombinant MAO-B is situated on the cytosolic face of the outer membrane in Pichia mitochondria
expression of MAOA in Pichia pastoris KM71 cell mitochondria
expression of MAOB in Pichia pastoris KM71 cell mitochondria
expression of mutant enzymes in Pichia pastoris
expression of wild-type and mutant MAOA in Pichia pastoris KM71 cell mitochondria
expression of wild-type and mutant MAOB in Pichia pastoris KM71 cell mitochondria
expression of wild-type MAO A and mutant MAO A C374A in Pichia pastoris
functional expression of zMAO in Pichia pastoris mitochondria with the gene encoding zMAO under control of the methanol oxidase promotor
-
high level expression in Pichia pastoris
-
high-level expression in Pichia pastoris, higher expression level than in Saccharomyces cerevisiae and higher level of homogeneity of the isolated enzyme
MAO A is encoded on the X chromosome
MAO A, expression in Pichia pastoris strain KM17H
MAO-A and MAO-B are products of two different genes
-
MAOA gene, genotyping in relation to autism spectrum disorder, overview
-
monoamine oxidase A is cloned into the high copy yeast expression vector pEG-KT, to generate a GST MAO-A fusion protein
-
not polymorphic for intron MAin2
not polymorphic for intron MAin2 (1 allele)
not polymorphic for intron MAin2 (2 alleles)
not polymorphic for intron MBin2
not polymorphic for intron MBin2 (1 allele)
not polymorphic for intron MBin2 (2 alleles)
overexpression of MAO-A in Pichia pastoris strain KM71
polymorphic for intron MAin2
polymorphic for intron MBin2