Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
-
brown fat of hypothyroid and hyperthyroid rats. Hypothyroidism increases MAO activity. T3 increased content of uncoupling protein 1 decreases activity of MAO
brenda
-
of adrenal gland
brenda
-
-
brenda
MAO-B elevation in mouse brain astrocytes results in Parkinsons pathology
brenda
MAO-A prevents basal epithelial cells from differentiating into secretory cells. Inhibition of MAO-A is a key factor in promoting this process. Increased expression of MAO-A in highgrade prostate cancer may be an important contributor to its de-differentiated phenotype
brenda
-
-
brenda
-
predominantly B form
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
environmentally relevant concentrations of Hg may influence the activities of ChE and MAO in the cerebral cortex
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
of lymphatic vessel
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
activity selectively increases in MAO-B activity in human gliomas when compared with meningiomas or non-tumoural tissue
brenda
-
predominantly B form
brenda
-
-
brenda
-
endothelial cells
brenda
activity selectively increases in MAO-B activity in human gliomas when compared with meningiomas or non-tumoural tissue
brenda
monoamine oxidase A promoter is regulated by the circadian-clock components BMAL1, NPAS2, and PER2. A mutation in the clock gene Per2 in mice leads to reduced expression and activity of MAOA in the mesolimbic dopaminergic system
brenda
-
-
brenda
-
-
brenda
-
brenda
-
acinar cells, entroacinar cells, follicular cells and parafolicular cells
brenda
-
-
brenda
-
-
brenda
-
-
brenda
MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Increased pineal MAOA activity might contribute to the reduced pineal melatonin production in Alzheimer's disease. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
is highly expressed in basal cells of the normal prostatic epithelium and in poorly differentiated, aggressive prostate cancer
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
male cell line
brenda
from females. The MAO-A gene is expressed from only one of the two alleles in each female cell
brenda
-
of duodenum, lung, blood vessels, spleen
brenda
in human subcutaneous adipose tissue, the adipocyte-enriched fraction exhibits seven-fold higher amine oxidase activity and contains 3- to 7-fold higher levels of mRNAs encoded by MAO-A and MAO-B genes than the stroma-vascular fraction. MAO-A gene accounts for the majority of the respective MAO and SSAO activities in human adipose tissue. Most of the SSAO and MAO found in adipose tissue originated from mature adipocytes
brenda
most of the monoamine oxidase found in adipose tissue originates from mature adipocytes
brenda
-
-
brenda
-
SSAO inhibition is not sufficient to impair fat deposition. Combined MAO and SSAO inhibition limits adiposity in non-obese as well as in obese rats
brenda
in human subcutaneous adipose tissue, the adipocyte-enriched fraction exhibits seven-fold higher amine oxidase activity and contains 3- to 7-fold higher levels of mRNAs encoded by MAO-A and MAO-B genes than the stroma-vascular fraction. MAO-A gene accounts for the majority of the respective MAO and SSAO activities in human adipose tissue. Most of the SSAO and MAO found in adipose tissue originated from mature adipocytes
brenda
most of the monoamine oxidase found in adipose tissue originates from mature adipocytes
brenda
-
-
brenda
-
brenda
-
-
brenda
-
brenda
alcoholics show significantly low levels of platelet MAO B activity, when compared with control subjects
brenda
association in girls between low platelet MAO-B activity and symptoms of Oppositional Defiant Disorder
brenda
both alcohol dependence and tobacco use might contribute to the lowering of platelet MAO-B activity, with the influence of smoking being much stronger. The decrease in MAO velocity is entirely due to inhibition by constituents of cigarette smoke, while alcohol use is responsible for the decrease in enzyme affinity
brenda
females with low platelet MAO-B activity show an increased risk of alcohol-related problem behaviour in an unfavourable environment
brenda
-
girls homozygous for the serotonin transporter gene promoter polymorphism long allele and with high platelet monoamine oxidase activity, both considered indicators of a higher capacity serotonin system, exhibit higher scores of drive for thinness
brenda
in boys, hemizygosity for the short MAO-A VNTR allele is associated with disruptive behavior
brenda
in the alcohol-dependent subjects concomitant cigarette smokers, but not snuff users, have significantly lower platelet MAO-B activity as compared to non-tobacco users
brenda
MAO B is the only isoform in platelets and lymphocytes
brenda
no systematic correlations exists between MAO-B activity and any dimensions of suicidal behaviour or psychopathology
brenda
-
platelet MAO activity may be a marker of severity of obsessive-compulsive disorder. Low platelet monoamine oxidase activity may be associated with aggressive obsessions in patients with obsessive-compulsive disorder
brenda
-
no significant gender-related difference in SSAO activity
brenda
-
no significant gender-related difference in SSAO activity
brenda
-
no significant gender-related difference in SSAO activity
brenda
-
no significant gender-related difference in SSAO activity
brenda
-
no significant gender-related difference in SSAO activity
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
dopaminergic cell clusters have low to moderate levels of MAO activity. The highest levels of MAO activity are detected in noradrenergic and serotonergic cell groups and the habenulointerpeduncular pathway, including its caudal projection to the medial ventral rhombencephalon
brenda
-
MAO expression and activity are located in or adjacent to serotonergic nuclei and their targets especially in the ventral hypothalamus
brenda
-
MAO expression and activity are located in or adjacent to serotonergic nuclei and their targets especially in the ventral hypothalamus
-
brenda
-
-
brenda
-
brenda
brain MAO A correlates inversely with the multidimensional personality questionnaire trait measure of aggression (but not with other personality traits)
brenda
MAO-B activity is significantly greater in glioblastoma multiforms than in postmortem control brains or meningiomas. There are no significant differences in MAO-B activity between glioblastoma multiforms and low-grade astrocytomas or anaplastic astrocytomas
brenda
MAO-B density seems to increase in suicide victims
brenda
MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism
brenda
no changes in baseline regional brain metabolism as a function of genotype indicating that, unchallenged, corticolimbic activity is not modulated by the MAO-A genotype
brenda
potential impact of a specific functional variant in MAO A gene on brain function subserving working memory. Genetic variation in MAO A is highly involved in both motor and cognitive inhibitory mechanisms by influencing the right ventro-lateral prefrontal cortex response
brenda
theoretical and experimental support for the notion that cigarette smoke-induced inhibition of MAO in the fetal brain, particularly when it occurs in combination with polymorphisms in the MAOA gene that lead to lower enzyme concentration in the brain, may result in brain morphologic and functional changes that enhance the risk of irritability, poor self-control and aggression in the offspring
brenda
age-related increase in MAO-B activity, whereas MAO-A activity remains constant
brenda
-
-
brenda
-
significant increase of cerebral MAO-B activity in scrapie-infected hamsters
brenda
-
-
brenda
-
brenda
-
brenda
-
-
brenda
-
in the brain MAO-B predominates and is associated with both glia and neurons, distribution in putamen, caudate nucleus, thalamus, hippocampus, cerebellum, temporal cortex, occipital cortex, parietal cortex, frontal cortex, white matter, and pons
brenda
-
brenda
-
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
long-term aluminium feeding results in activation of monoamine oxidase A up to 1.9fold
brenda
long-term aluminium feeding results in activation of monoamine oxidase B up to 3.8fold
brenda
-
normal brain aging is associated with significant increases in the activity of monoamine oxidase. Dehydroepiandrosterone treatment significantly decreases monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in brain regions of aging rats
brenda
repeated nandrolone decanoate administration reduces activity of monoamine oxidase A
brenda
repeated nandrolone decanoate administration reduces activity of monoamine oxidase B
brenda
-
-
brenda
-
brenda
-
MAO-A and MAO-B
brenda
-
recombinant isozymes MAO A and MAO B, expressed in baculovirus-infected insect cells BTI-TN-5B1-4
brenda
-
brenda
unilateral injection of 6-hydroxydopamine produces no change in striatal MAO-A or MAO-B activity, but following the double lesion, MAO-B activity increases by 37.5% with no change in MAO-A activity
brenda
-
of blood vessels
brenda
MAO A is prevalent in fibroblasts and placental tissue
brenda
-
predominance of monoamine oxidase A, mRNA for monoamine oxidase B is present but the protein itself is undetected with beta-phenylethylamine as substrate
brenda
-
increase in monoamine oxidase activity in both middle aged and aged rats, compared to young rats
brenda
-
embryonic
brenda
-
-
brenda
-
MAO expression and activity are located in or adjacent to serotonergic nuclei and their targets especially in the ventral hypothalamus
brenda
-
MAO expression and activity are located in or adjacent to serotonergic nuclei and their targets especially in the ventral hypothalamus
-
brenda
-
-
brenda
-
-
brenda
-
podocyte, collecting duct
brenda
-
-
brenda
-
alpha cells
brenda
-
development of MAO expression follows a similar time course as the serotonin system
brenda
-
development of MAO expression follows a similar time course as the serotonin system
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
394551, 394553, 394555, 394564, 394565, 394588, 654840, 655288, 656957, 657163, 711164, 711464, 724966, 394552 brenda
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
Neogale vison
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
394554, 394558, 394559, 394562, 394565, 394567, 394569, 394574, 655523, 657397, 706602 brenda
-
brenda
-
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
-
brenda
-
predominantly B form
brenda
MAO B is the only isoform in platelets and lymphocytes
brenda
-
brenda
-
SK-N-BE(2)-C
brenda
-
-
brenda
-
brenda
MAO A is prevalent in fibroblasts and placental tissue
brenda
-
MAO-A
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
additional information
-
no activity in connective tissue of heart and pancreas, endothelial cells of blood vessels, Brunner gland cells, interstitial cells of kidney, gamma cells of of Langerhans islets, alpha-cells of Langerhans islets
brenda
additional information
-
predominance of monoamine oxidase A, mRNA for monoamine oxidase B is present but the protein itself is undetected with beta-phenylethylamine as substrate
brenda