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1.4.7.1: glutamate synthase (ferredoxin)

This is an abbreviated version!
For detailed information about glutamate synthase (ferredoxin), go to the full flat file.

Word Map on EC 1.4.7.1

Reaction

2 L-glutamate +

oxidized ferredoxin
=
L-glutamine
+
2-oxoglutarate
+
reduced ferredoxin
+ 2 H+

Synonyms

abc1, At5g04140, ES7, Fd-dependent glutamate synthase, Fd-GOGAT, Fd-GOGAT1, FdGOGAT, ferredoxin-dependent GltS, ferredoxin-dependent glutamate synthase, ferredoxin-dependent glutamate synthase1, ferredoxin-dependent glutamine 2-oxoglutarate aminotransferase, ferredoxin-dependent GOGAT, ferredoxin-glutamate synthase, ferredoxin-GOGAT, gltB, GltS, Glu1, glutamate synthase, glutamate synthase (ferredoxin-dependent), glutamine 2-oxoglutarate amidotransferase, glutamine:2-oxoglutarate amidotransferase, glutamine:oxoglutarate amidotransferase, GOGAT, lc7

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.7 With an iron-sulfur protein as acceptor
                1.4.7.1 glutamate synthase (ferredoxin)

Inhibitors

Inhibitors on EC 1.4.7.1 - glutamate synthase (ferredoxin)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-oxoglutarate
-
at high concentrations
3-(3,4-dichlorophenyl)-1,1-dimethylurea
-
-
3-phosphoglycerate
-
-
3-phosphoserine
-
competitive inhibition
5-oxo-L-norleucine
covalent
6-diazo-5-oxo-L-norleucine
-
6-diazo-5-oxo-norleucine
aspartate
-
competitive inhibition
Atebrin
-
1 mM, 45% inhibition
azaserine
Bromocresol green
-
1 mM, 89% inhibition
Cd2+
-
5 mM, 69% inhibition
Co2+
-
5 mM, 65% inhibition
cycloheximide
-
complete disappearance of enzyme in roots and 90% decrease in leaves after 24 h
glycine
glycolate
-
20 mM, more than 60% inhibition
glyoxylate
-
20 mM, more than 60% inhibition
iodoacetamide
-
90% inactivation after 15 h, L-glutamine protects from inactivation
L-arginine
-
-
L-methionine
-
-
L-ornithine
-
-
L-serine
L-threonine
-
-
Mn2+
-
5 mM, 45% inhibition
N-ethylmaleimide
Ni2+
-
5 mM, 73% inhibition
p-chloromercuribenzoate
-
0.1 mM, complete inhibition
p-chloromercuriphenylsulfonate
-
0.1 mM, complete inhibition
p-hydroxymercuribenzoate
additional information
-
not inhibitory: chloramphenicol
-