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1.5.1.2: pyrroline-5-carboxylate reductase

This is an abbreviated version!
For detailed information about pyrroline-5-carboxylate reductase, go to the full flat file.

Word Map on EC 1.5.1.2

Reaction

L-proline
+
NAD(P)+
=
1-pyrroline-5-carboxylate
+
NAD(P)H
+
H+

Synonyms

1-pyrroline-5-carboxylate reductase, aldimine reductase, DELTA1-pyrroline-5-carboxylate reductase, DELTA1-pyrroline-5-carboxylate reductase 2, L-proline oxidase, L-proline-NAD(P)+ 5-oxidoreductase, L-proline:NAD(P)+ 5-oxidoreductase, MTR_7g090160, NADPH-L-DELTA'-pyrroline carboxylic acid reductase, P5C reductase, P5CDH, P5CR, PO, POX, PROC, proline oxidase, Pycr1, PYCR2, Pyr5C reductase, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylate reductase, reductase, pyrroline-5-carboxylate, TcCLB.509207.90

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.2 pyrroline-5-carboxylate reductase

pH Optimum

pH Optimum on EC 1.5.1.2 - pyrroline-5-carboxylate reductase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10.2
-
proline dehydrogenase activity
10.3
-
activity assay, reverse reaction
6
-
cofactor NADH
6.05
-
-
6.5 - 7.1
-
-
6.7 - 7.4
-
-
6.8 - 7.5
-
pyrroline-5-carboxylate reductase activity
7 - 7.5
7 - 7.6
-
-
7 - 8
7.2
-
activity assay
7.3
cofactor NADH
8.4
cofactor NADPH
9.8 - 10.4
-
proline dehydrogenase activity