1.5.1.3: dihydrofolate reductase

This is an abbreviated version, for detailed information about dihydrofolate reductase, go to the full flat file.

Reaction

5,6,7,8-tetrahydrofolate
+
NADP+
=
7,8-dihydrofolate
+
NADPH
+
H+

Synonyms

5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, 7,8-dihydrofolate reductase, dehydrogenase, tetrahydrofolate, DHFR, DHFR type IIIC, DHFR-TS, dihydrofolate reductase, dihydrofolate reductase-thymidylate synthase, dihydrofolate reductase:thymidylate synthase, dihydrofolic acid reductase, dihydrofolic reductase, EC 1.5.1.4, ecDHFR, folA3, folic acid reductase, folic reductase, FolM, hDHFR-1, hDHFR-2, HjDHFR, hvDHFR1, hvDHFR2, mjDHFR, myDHFR, NADPH-dihydrofolate reductase, ppDHFR, pteridine reductase:dihydrofolate reductase, R-plasmid-encoded dihydrofolate reductase, R67 DHFR, R67 dihydrofolate reductase, reductase, dihydrofolate, S3DHFR, spDHFR, svDHFR, tetrahydrofolate dehydrogenase, thymidylate synthase-dihydrofolate reductase, thymidylate synthetase-dihydrofolate reductase, Trimethoprim resistance protein, TS-DHFR

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.3 dihydrofolate reductase