1.5.1.30: flavin reductase (NADPH)

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For detailed information about flavin reductase (NADPH), go to the full flat file.

Reaction

Synonyms

alkanesulfonate FMN reductase, ArsH, azoreductase, AZR�, biliverdin IXbeta reductase, biliverdin reductase B, biliverdin reductase-B, Biliverdin-IX beta-reductase, BLVRB, CysJ, EC 1.6.8.2, FAD-dependent NADP-reductase, flavin oxidoreductase, flavin reductase, flavin reductase 1, flavin reductase Nr1, flavin reductase P, FLR, FR1, Frb, Frd188, frd2, fre, Fre oxidoreductase, Fre-1, FRG/FRaseI, FRGvf, FRP, FRPvh, GHBP, Green heme binding protein, HpaC, ipa-43d, LuxG, More, NAD(P)H-dependent H2O2-forming flavin reductase, NAD(P)H:flavin-oxidoreductase, NADPH-dependant FMN reductase, NADPH-dependent diaphorase, NADPH-flavin oxidoreductase, NADPH-flavin reductase, NADPH-FMN oxidoreductase, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NADPH-specific flavin reductase, NADPH:FAD oxidoreductase, NADPH:flavin oxidoreductase, NADPH:FMN oxidoreductase, NfrA1, nitro/flavin reductase, non-luminescent-bacterial NfsA/Frp-type enzyme, SsuE, TVAG_517010

ECTree

     1 Oxidoreductases

         1.5 Acting on the CH-NH group of donors

             1.5.1 With NAD⁺ or NADP⁺ as acceptor

                1.5.1.30 flavin reductase (NADPH)

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Results	in table
7	Activating Compound
300	AA Sequence
1	Application
1	CAS Registry Number
24	Cloned(Commentary)
65	Cofactor
5	Crystallization (Commentary)
29	Disease/ Diagnostics
28	General Information
2	General Stability
36	Inhibitors
13	kcat/KM [mM/s]
8	Ki Value [mM]
64	KM Value [mM]
4	Localization
8	Metals/Ions
31	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
77	Organism
4	Pathway
31	PDB ID
13	pH Optimum
2	pH Range
2	pH Stability
2	pI Value
17	Protein Variants
24	Purification (Commentary)
12	Reaction
5	Reaction Type
59	Reference
2	Renatured (Commentary)
19	Source Tissue
11	Specific Activity [micromol/min/mg]
1	Storage Stability
129	Substrates and Products (Substrate)
31	Subunits
107	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
27	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.5.1.30 - flavin reductase (NADPH)

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.37

Homo sapiens

-

pH 7.0, 25°C

392188

107

Streptomyces viridifaciens

-

-

392301

122

Rhodococcus erythropolis

-

-

392304

133

Rhodococcus erythropolis

-

flavin reductase from recombinant Escherichia coli

392304

141

Streptomyces viridifaciens

-

without N-terminal His-tag

392301

22

Entamoeba histolytica

-

-

392296

42.1

Bacillus subtilis

-

FMN reduction with NADH, pH 6.0, 50°C

699057

52.5

Bacillus subtilis

-

purified recombinant untagged enzyme, pH 7.0, 23°C

742109

53

Bacillus subtilis

-

-

392302

85.5

Bacillus subtilis

-

FMN reduction with NADPH, pH 6.0, 50°C

699057

88

Vibrio harveyi

-

-

392297