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1.5.3.16: spermine oxidase

This is an abbreviated version!
For detailed information about spermine oxidase, go to the full flat file.

Word Map on EC 1.5.3.16

Reaction

spermine
+
O2
 +
H2O
=
spermidine
 +
3-aminopropanal
 +
H2O2

Synonyms

AtPAO1, AtPAO4, AtPAO5, EC 1.5.3.11, Fms1 protein, GhPAO, hSMO, MmSMO, mSMO, mSMOalpha, mSMOmu, PAO, PAO1, PAO4, PAO5, PAO6, PAO7, PAOh1, PAOh1/SMO, SelPAO5, SMO, SMO(PAOh1), SMO/PAOh1, SMO5, SMOX, spermine oxidase, Spm oxidase, thermospermine oxidase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.16 spermine oxidase

KI Value

KI Value on EC 1.5.3.16 - spermine oxidase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0117 - 1
1,12-diaminododecane
0.293
1,8-diaminooctane
pH 8.0, substrate: spermine
0.0075
6,6'-[ethane-1,2-diyldi(piperidine-4,1-diyl)]bis[N-[(2-methoxyphenyl)methyl]hexan-1-amine]
pH 7.5, 37°C
-
0.147
agmatine
pH 8.0, substrate: spermine
0.38
bis(ethyl)norspermine
0.00055 - 0.0038
Chlorhexidine
0.0004 - 0.0007
guazatine
0.02
MDL 27695
-
pH 8.5, 37°C
0.0009
MDL 72145
-
-
0.063 - 0.1373
MDL72527
0.0012
methoctramine
pH 7.5, 37°C
-
0.063
N,N' -bis(2,3-butadienyl)-1,4-butanediamine
-
pH 8.5, 25°C
0.063
N,N1-bis(2,3-butadienyl)-1,4-butanediamine
-
0.004 - 0.046
N-prenylagmatine
0.0046
N1,N1'-(pentane-1,5-diyl)bis[N6-[(2-methoxyphenyl)methyl]hexane-1,6-diamine]
pH 7.5, 37°C
-
0.063
N1,N4-bis(2,3-butadienyl)-1,4-butanediamine
-
isozyme SMOalpha, pH 8.0, temperature not specified in the publication
0.0019
N1,N7-bis(6-[[(2-methoxyphenyl)methyl]amino]hexyl)heptane-1,7-diamine
pH 7.5, 37°C
-
0.085
N1-ethyl-N11-(cyclopropyl)-methyl-4,8-diazaundecane
0.546
spermidine
pH 8.0, substrate: spermine
0.172
triethylenetetramine
-
pH 7.2, 37°C, with spermine as substrate