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1.5.99.14: 6-hydroxypseudooxynicotine dehydrogenase

This is an abbreviated version!
For detailed information about 6-hydroxypseudooxynicotine dehydrogenase, go to the full flat file.

Reaction

1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one
+
acceptor
+
H2O
=
1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one
+
reduced acceptor

Synonyms

KdhA, KdhB, KdhC, KdhL, KdhM, KdhS, PNO

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.99 With unknown physiological acceptors
                1.5.99.14 6-hydroxypseudooxynicotine dehydrogenase

Systematic Name

Systematic Name on EC 1.5.99.14 - 6-hydroxypseudooxynicotine dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one:acceptor 6-oxidoreductase (hydroxylating)
Contains a cytidylyl molybdenum cofactor [3]. The enzyme, which participates in the nicotine degradation pathway, has been characterized from the soil bacterium Arthrobacter nicotinovorans [1,2].