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1.6.1.2: NAD(P)+ transhydrogenase (Re/Si-specific)

This is an abbreviated version!
For detailed information about NAD(P)+ transhydrogenase (Re/Si-specific), go to the full flat file.

Word Map on EC 1.6.1.2

Reaction

NADPH
+
NAD+
=
NADP+
+
NADH

Synonyms

dII, dIII, energy-linked transhydrogenase, energy-linked, mitochondrial transhydrogenase, H+-thase, mitochondrial transhydrogenase, NAD transhydrogenase, NAD(P) transhydrogenase, NADH transhydrogenase, NADH-NADP-transhydrogenase, NADPH transhydrogenase, NADPH-NAD oxidoreductase, NADPH-NAD transhydrogenase, NADPH:NAD+ transhydrogenase, nicotinamide adenine dinucleotide (phosphate) transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT, PNT, PntAB, proton-translocating nicotinamide nucleotide transhydrogenase, proton-translocating transhydrogenase, pyridine nucleotide transferase, pyridine nucleotide transhydrogenase, reversible mitochondrial membrane-associated transhydrogenase, transhydrogenase, transhydrogenase, nicotinamide adenine dinucleotide (phosphate)

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.1 With NAD+ or NADP+ as acceptor
                1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)

Cloned

Cloned on EC 1.6.1.2 - NAD(P)+ transhydrogenase (Re/Si-specific)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
as Corynebacterium glutamicum does not possess membrane-integral nicotinamide nucleotide transhydrogenase, the Escherichia coli pntAB genes are expressed in the genetically defined Corynebacterium glutamicum lysine-producing strain DM1730, resulting in membrane-associated transhydrogenase activity of 0.7 U/mg proteine. Expression of the pntAB genes in Corynebacterium glutamicum improves L-lysine formation. In contrast, pntAB expression has a negative effect on growth and glutamate production of Corynebacterium glutamicum wild type
-
dI and native and E155W mutant of dIII expressed in Escherichia coli
-
dIII domain expressed in Escherichia coli
domains dIII and dI expressed in Escherichia coli, recombinant protein lacks the membrane spanning dII domain
-
expressed in Corynebacterium glutamicum strain ATCC 13032
expressed in Escherichia coli as His-tag fusion protein
expressed in Escherichia coli B834 (DE3) cells
expressed in Escherichia coli BL21(DE3) cells
expression in Escherichia coli
-
expression in Escherichia coli on multicopy plasmid
-
expression of domain I in Escherichia coli
-
expression of domain I Y235N and Y235F mutants in Escherichia coli
-
expression of domain III-domain I protein in Escherichia coli
-
expression of domains I and III in Escherichia coli
-
expresssion of domain III in Escherichia coli
-
gene Nnt, overexpression of C-terminally V5-tagged full-length cDNA in the macrophage-like cell line RAW264.7, real-time PCR expression analysis
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