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1.6.3.2: NAD(P)H oxidase (H2O-forming)

This is an abbreviated version!
For detailed information about NAD(P)H oxidase (H2O-forming), go to the full flat file.

Reaction

2 NADPH +

H+
+
O2
= 2 NADP+ + 2 H2O

Synonyms

KOD1, NAD(P)H oxidase, NOX, NOXtp, TK1299

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.3 With oxygen as acceptor
                1.6.3.2 NAD(P)H oxidase (H2O-forming)

Inhibitors

Inhibitors on EC 1.6.3.2 - NAD(P)H oxidase (H2O-forming)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cu2+
-
92% inhibition at 0.1 mg/ml
CuSO4
0.2 mM, 97% inhibition
H2O2
0.5 mM, 50% inhibition
Hg2+
-
complete inhibition at 0.1 mg/ml
HgCl2
0.5 mM, 80% inhibition
p-chloromercuribenzoate
0.05 mM, complete inhibition
p-mercuribenzoate
-
99% inhibition at 0.1 mg/ml
Quinacrine
Quinine
0.2 mM, 50% inhibition
Zn2+
-
89% inhibition at 0.1 mg/ml
ZnSO4
0.1 mM, 98% inhibition
additional information
no inhibition by EDTA
-