1.6.5.10: NADPH dehydrogenase (quinone)
This is an abbreviated version!
For detailed information about NADPH dehydrogenase (quinone), go to the full flat file.
Word Map on EC 1.6.5.10
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1.6.5.10
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neutrophil
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endothelial
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p47phox
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phagocyte
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apocynin
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dismutase
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artery
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gp91phox
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cardiovascular
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nicotinamide
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hypertension
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angiotensin
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catalase
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oxidases
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cardiac
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leukocyte
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phorbol
-
monocyte
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mapks
-
sod
-
aortic
-
granulomatous
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diphenyleneiodonium
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diphenylene
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pma
-
iodonium
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rac1
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atherosclerosis
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chemiluminescence
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phagocytosis
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xanthine
-
polymorphonuclear
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myristate
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microglial
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myeloperoxidase
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ii-induced
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dihydroethidium
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endothelium-dependent
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flavocytochrome
-
zymosan
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peroxynitrite
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phagosomes
-
tempol
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fmlp
-
ros-dependent
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microbicidal
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nadph-oxidase
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nitrotyrosine
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lucigenin
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medicine
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fmlp-induced
- 1.6.5.10
- neutrophil
- endothelial
- p47phox
- phagocyte
- apocynin
- dismutase
- artery
- gp91phox
- cardiovascular
- nicotinamide
- hypertension
- angiotensin
- catalase
- oxidases
- cardiac
- leukocyte
-
phorbol
- monocyte
- mapks
- sod
- aortic
- granulomatous
- diphenyleneiodonium
-
diphenylene
- pma
- iodonium
- rac1
- atherosclerosis
-
chemiluminescence
-
phagocytosis
- xanthine
-
polymorphonuclear
- myristate
- microglial
- myeloperoxidase
-
ii-induced
- dihydroethidium
-
endothelium-dependent
-
flavocytochrome
- zymosan
- peroxynitrite
-
phagosomes
-
tempol
- fmlp
-
ros-dependent
-
microbicidal
- nadph-oxidase
-
nitrotyrosine
- lucigenin
- medicine
-
fmlp-induced
Reaction
Synonyms
AKR1C9, ArsH, azoreductase, CBR4, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate (quinone), EC 1.6.99.6, MdaB, More, NADPH oxidase, NADPH quinone oxidoreductase, NADPH quinone oxidoreductase 1, NADPH quinone reductase, NADPH-dependent quinone reductase, NADPH-quinone oxidoreductase, NADPH:quinone oxidoreductase 1, NQO1, PA1225, PpAzoR, XAC2229, Zta1p
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Specific Activity
Specific Activity on EC 1.6.5.10 - NADPH dehydrogenase (quinone)
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0.0006
0.0007
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TNFalpha and LPS inhibit the beta-naphthoflavone induced increase in activity
0.0016
substrate 9,10-phenanthrenenquinone, mutant Y55S, pH 6.0, 25°C
0.0018
substrate 9,10-phenanthrenenquinone, mutant Y55F, pH 6.0, 25°C
1.097
-
activity of purified cytochrome b558 reconstituted with neutrophil membrane phospholipids, activation with arachidonic acid
1.258
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activity of purified cytochrome b558 reconstituted with neutrophil membrane phospholipids, activation with sodiumdodecylsulfate
additional information
additional information
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90300 units/mg, 1 unit is defined as that amount of enzyme causing an absorption change of 0.001 units/min at the specific wavelength