1.6.5.10: NADPH dehydrogenase (quinone)
This is an abbreviated version!
For detailed information about NADPH dehydrogenase (quinone), go to the full flat file.
Word Map on EC 1.6.5.10
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1.6.5.10
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neutrophil
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endothelial
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p47phox
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phagocyte
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apocynin
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dismutase
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artery
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gp91phox
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cardiovascular
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nicotinamide
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hypertension
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angiotensin
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catalase
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oxidases
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cardiac
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leukocyte
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phorbol
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monocyte
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mapks
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sod
-
aortic
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granulomatous
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diphenyleneiodonium
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diphenylene
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pma
-
iodonium
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rac1
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atherosclerosis
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chemiluminescence
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phagocytosis
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xanthine
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polymorphonuclear
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myristate
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microglial
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myeloperoxidase
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ii-induced
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dihydroethidium
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endothelium-dependent
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flavocytochrome
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zymosan
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peroxynitrite
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phagosomes
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tempol
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fmlp
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ros-dependent
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microbicidal
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nadph-oxidase
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nitrotyrosine
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lucigenin
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medicine
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fmlp-induced
- 1.6.5.10
- neutrophil
- endothelial
- p47phox
- phagocyte
- apocynin
- dismutase
- artery
- gp91phox
- cardiovascular
- nicotinamide
- hypertension
- angiotensin
- catalase
- oxidases
- cardiac
- leukocyte
-
phorbol
- monocyte
- mapks
- sod
- aortic
- granulomatous
- diphenyleneiodonium
-
diphenylene
- pma
- iodonium
- rac1
- atherosclerosis
-
chemiluminescence
-
phagocytosis
- xanthine
-
polymorphonuclear
- myristate
- microglial
- myeloperoxidase
-
ii-induced
- dihydroethidium
-
endothelium-dependent
-
flavocytochrome
- zymosan
- peroxynitrite
-
phagosomes
-
tempol
- fmlp
-
ros-dependent
-
microbicidal
- nadph-oxidase
-
nitrotyrosine
- lucigenin
- medicine
-
fmlp-induced
Reaction
Synonyms
AKR1C9, ArsH, azoreductase, CBR4, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate (quinone), EC 1.6.99.6, MdaB, More, NADPH oxidase, NADPH quinone oxidoreductase, NADPH quinone oxidoreductase 1, NADPH quinone reductase, NADPH-dependent quinone reductase, NADPH-quinone oxidoreductase, NADPH:quinone oxidoreductase 1, NQO1, PA1225, PpAzoR, XAC2229, Zta1p
ECTree
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Systematic Name
Systematic Name on EC 1.6.5.10 - NADPH dehydrogenase (quinone)
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NADPH:(quinone-acceptor) oxidoreductase
A flavoprotein [1, 2]. The enzyme from Escherichia coli is specific for NADPH and is most active with quinone derivatives and ferricyanide as electron acceptors [3].
Menaquinone can act as acceptor. The enzyme from hog liver is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol [1].