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1.6.5.9: NADH:quinone reductase (non-electrogenic)

This is an abbreviated version!
For detailed information about NADH:quinone reductase (non-electrogenic), go to the full flat file.

Word Map on EC 1.6.5.9

Reaction

NADH
+
H+
+
a quinone
=
NAD+
+
a quinol

Synonyms

alternative external NADH dehydrogenase, alternative NADH dehydrogenase, alternative NADH-quinone oxidoreductase, alternative NADH:quinone reductase, alternative NADH:ubiquinone oxidoreductase, alternative rotenone-insensitive NADH:Q oxidoreductase, CathTA2_0279, Cgl1465, EC 1.6.5.11, EC 1.6.99.5, external alternative NADH dehydrogenase, external alternative NADH: ubiquinone oxidoreductase, external NADH:ubiquinone oxidoreductase, external rotenone-insensitive NADH dehydrogenase, internal alternative NADH dehydrogenase, internal alternative NADH: ubiquinone oxidoreductase, internal alternative NADH:ubiquinone oxidoreductase, Internal NADH dehydrogenase, internal rotenone-insensitive NADH dehydrogenase, NADH dehydrogenase, NADH dehydrogenase-2, NADH-ubiquinone oxidoreductase, NADH: ubiquinone oxidoreductase, NADH: ubiquinone-2 oxidoreductase, NADH:Q6 oxidoreductase, NADH:ubiquinone reductase (non-electrogenic), NADHQ2, NDA, NDB, NdeA, NdeA-B, NDH, NDH-2, NDH-II, NDH2, NDH2e, NDH2i, Ndi1, NdiA, NDX, non-proton pumping type II NADH dehydrogenase, non-proton-pumping NADH dehydrogenase, rotenone-insensitive NADH dehydrogenase, rotenone-insensitive NADH-ubiquinone oxidoreductase

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.5 With a quinone or similar compound as acceptor
                1.6.5.9 NADH:quinone reductase (non-electrogenic)

Cloned

Cloned on EC 1.6.5.9 - NADH:quinone reductase (non-electrogenic)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) pLysS cells
-
expressed in Escherichia coli BL21(DE3)pLysS cells
-
expressed in Escherichia coli membranes
gene Ndi1, inducible NDI1 enzyme expression in Drosophila melanogaster mitochondria of different cells and tissues. Expression of Ndi1 in fly mitochondria leads to an increase in NADH-ubiquinone oxidoreductase activity, oxygen consumption and ATP levels. In addition, exogenous Ndi1 expression results in increased CO2 production in living flies. Targeted expression of Ndi1 in fly neurons significantly increases lifespan without compromising fertility or physical activity
-
recombinant expression of His-tagged NDH-2
-