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1.6.99.1: NADPH dehydrogenase

This is an abbreviated version!
For detailed information about NADPH dehydrogenase, go to the full flat file.

Word Map on EC 1.6.99.1

Reaction

NADPH
+
H+
+
acceptor
=
NADP+
+
reduced acceptor

Synonyms

2-cyclohexen-1-one, dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate, diaphorase, dihydronicotinamide adenine dinucleotide phosphate dehydrogenase, EBP, Estrogen-binding protein, NADP-d, NADPH diaphorase, NADPH-d, NADPH-dehydrogenase, NADPH-dependent cyclohexenone reductase, NADPH-dependent diaphorase, NADPH-diaphorase, NADPH-methemoglobin reductase, NADPH2-dehydrogenase, NCR, nicotinamide adenine dinucleotide phosphate diaphorase, nitric oxide synthase, old yellow enzyme, Old yellow enzyme homolog, OYE, OYE1, OYE2, OYE3, reduced nicotinamide adenine dinucleotide phosphate dehydrogenase, SYE4, TPNH dehydrogenase, TPNH-diaphorase, triphosphopyridine diaphorase, triphosphopyridine nucleotide diaphorase, YqjM

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.99 With unknown physiological acceptors
                1.6.99.1 NADPH dehydrogenase

Inhibitors

Inhibitors on EC 1.6.99.1 - NADPH dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(9R,13R)-12-oxophytodienoate
-
-
alpha-NADPH
-
diaphorase activity of neuron somata
L-N5-(1-iminoethyl)Orn
-
1 mM 63% inhibition
monomethyl-L-Arg acetate
-
1 mM, 14% inhibition
NG-nitro-L-Arg
-
3 mM, 53% inhibition
Ngamma-monomethyl-L-Arg
-
1 mM, 14% inhibition
Ngamma-nitro-L-arginine
-
-
additional information
-
the traditional chinese medicine Nao Yi An, a complex derived from materials of animal and plant origin, can selectively inhibit the induction and thus, potentially play a neuroprotective role
-