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1.7.1.10: hydroxylamine reductase (NADH)

This is an abbreviated version!
For detailed information about hydroxylamine reductase (NADH), go to the full flat file.

Word Map on EC 1.7.1.10

Reaction

NH3
+
NAD+
+
H2O
=
hydroxylamine
+
NADH
+
H+

Synonyms

ammonium dehydrogenase, EC 1.6.6.11, hybrid cluster protein, N-hydroxy amine reductase, NADH-hydroxylamine reductase, PG0893, reductase, hydroxylamine

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.10 hydroxylamine reductase (NADH)

Inhibitors

Inhibitors on EC 1.7.1.10 - hydroxylamine reductase (NADH)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate
-
1.5 mM, 68% inhibition, hydroxylamine protects
2,2'-dipyridyl
8-hydroxyquinoline
Antimycin 1
-
0.1 mM, 26% inhibition of hydroxylamine reductase activity
Bromelain
-
-
-
CaCl2
-
reactivation by washing
deoxycholic acid
-
-
dinitrophenol
-
0.1 mM, 80% inhibition of hydroxylamine reductase activity
dithioerythritol
-
-
Duponol C
-
-
HgCl2
hydrazine
-
1 mM, complete inhibition
Iodine
-
0.5 mM, 80% inhibition, preincubation with hydroxylamine protects
KCl
-
reactivation by washing
Murine phospholipase
-
-
-
N-ethylmaleimide
N-Methyl hydroxylamine
-
-
N-Methylhydroxylamine
NaCl
-
reactivation by washing
NADH
-
inhibits in absence of hydroxylamine
nitrite
-
nitrite and hydroxylamine reductase activity are associated with the same enzyme, nitrite and hydroxylamine are competitive for the same binding site
o-phenanthroline
p-chloromercuribenzoate
p-hydroxymercuribenzoate
papain
-
-
-
potassium cyanide
-
-
potassium ethyl xanthate
potassium thiocyanate
-
0.1 mM, 90% inhibition of hydroxylamine reductase activity, nitrite reductase activity is not inhibited
Propanol
-
-
Rose bengal
-
0.5 mM, 94% inhibition
rotenone
-
0.1 mM, 52% inhibition of hydroxylamine reductase activity
Salicylaldoxime
Sodium arsenate
-
-
Sodium diethyl dithiocarbamate
Subtilopeptidase A
-
-
-
sulfite
Trypsin
-
-
-
Uranyl acetate
-
ATP, ADP, sodium diphosphate restores activity
additional information
-