1.7.1.7: GMP reductase

This is an abbreviated version!
For detailed information about GMP reductase, go to the full flat file.

Word Map on EC 1.7.1.7

1.7.1.7

purine

imp

salvage

hypoxanthine

impdhs

hypoxanthine-guanine

adenylosuccinate

medicine

drug development

Reaction

Synonyms

EC 1.6.6.8, GMPR, GMPR-I, GMPR-II, GMPR2, guaC, Guanosine 5'-monophosphate oxidoreductase, guanosine 5'-monophosphate reductase, guanosine monophosphate reductase, guanosine monophosphate reductase 2, guanosine-5'-monophosphate reductase, guanylate reductase, HsGMPR1, HsGMPR2, LmGMPR, Lmj17.0725, LMJF_17_0725, NADPH:GMP oxidoreductase (deaminating), reductase, guanylate, Tb927.5.2080, TbGMPR, TcGMPR, TCIL3000_5_1940

ECTree

1 Oxidoreductases

1.7 Acting on other nitrogenous compounds as donors

1.7.1 With NAD⁺ or NADP⁺ as acceptor

1.7.1.7 GMP reductase

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Results	in table
10	Activating Compound
9196	AA Sequence
3	Application
1	CAS Registry Number
13	Cloned(Commentary)
27	Cofactor
3	Crystallization (Commentary)
45	Disease/ Diagnostics
1	Expression
13	General Information
1	General Stability
4	IC50 Value
75	Inhibitors
2	kcat/KM [mM/s]
10	Ki Value [mM]
40	KM Value [mM]
5	Localization
9	Metals/Ions
16	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
46	Organism
4	Pathway
32	PDB ID
12	pH Optimum
4	pH Range
1	pI Value
1	Posttranslational Modification
5	Protein Variants
14	Purification (Commentary)
6	Reaction
4	Reaction Type
40	Reference
44	Source Tissue
16	Specific Activity [micromol/min/mg]
5	Storage Stability
48	Substrates and Products (Substrate)
10	Subunits
53	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
4	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.7.1.7 - GMP reductase

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0.003 - 0.0076

Mycoplasma mycoides

activity in extracts of cells grown on different media

394286

0.0051

Bacillus subtilis

activity in wild-type

0.0052

0.078

0.35

0.564

0.66

pH 7.8, 25°C

0.8

activity in wild-type

394279

21.7

Trypanosoma brucei brucei

Q57ZS7

pH 8.0, 35°C, with NaCl

743568

30.6

Trypanosoma brucei brucei

Q57ZS7

pH 8.0, 35°C, with NH4Cl

743568

4.6

Escherichia coli

activity in guaC mutant harbouring a guaC plasmid

394279

43.8

Trypanosoma brucei brucei

Q57ZS7

pH 8.0, 35°C, with KCl

743568

additional information

4 entries