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1.7.1.7: GMP reductase

This is an abbreviated version!
For detailed information about GMP reductase, go to the full flat file.

Word Map on EC 1.7.1.7

Reaction

IMP
+
NH3
+
NADP+
=
GMP
+
NADPH
+
H+

Synonyms

EC 1.6.6.8, GMPR, GMPR-I, GMPR-II, GMPR2, guaC, Guanosine 5'-monophosphate oxidoreductase, guanosine 5'-monophosphate reductase, guanosine monophosphate reductase, guanosine monophosphate reductase 2, guanosine-5'-monophosphate reductase, guanylate reductase, HsGMPR1, HsGMPR2, LmGMPR, Lmj17.0725, LMJF_17_0725, NADPH:GMP oxidoreductase (deaminating), reductase, guanylate, Tb927.5.2080, TbGMPR, TcGMPR, TCIL3000_5_1940

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.7 GMP reductase

Substrates Products

Substrates Products on EC 1.7.1.7 - GMP reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
dGMP + NADPH + H+
dIMP + NH3 + NADP+
show the reaction diagram
dGMP is a poor substrate
-
-
r
dIMP + NH3 + NADP+
dGMP + NADPH + H+
show the reaction diagram
dIMP is a poor substrate
-
-
r
GMP + NADPH + H+
IMP + NH3 + NADP+
show the reaction diagram
IMP + NH3 + NADP+
GMP + NADPH + H+
show the reaction diagram
NADPH + guanosine 5'-phosphate
NADP+ + inosine 5'-phosphate + NH3
show the reaction diagram
NADPH + H+ + guanosine 5'-phosphate
NADP+ + inosine 5'-phosphate + NH3
show the reaction diagram
-
-
-
-
?
additional information
?
-
enzyme nucleotide bindng analysis, nucleotide binding alters the quarternary structure of the enzyme, overview
-
-
?