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1.7.1.9: nitroquinoline-N-oxide reductase

This is an abbreviated version!
For detailed information about nitroquinoline-N-oxide reductase, go to the full flat file.

Reaction

4-(hydroxyamino)quinoline N-oxide
+ 2 NAD(P)+ +
H2O
=
4-Nitroquinoline N-oxide
+ 2 NAD(P)H + 2 H+

Synonyms

4-nitroquinoline 1-oxide reductase, 4NQO reductase, EC 1.6.6.10, NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.9 nitroquinoline-N-oxide reductase

Specific Activity

Specific Activity on EC 1.7.1.9 - nitroquinoline-N-oxide reductase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.032
-
activity in cheek mucosa
0.07
-
activity in corpus ventriculi and pyloric antrum
0.084
-
activity in tongue mucosa
0.1
-
activity in duodenum
0.12
-
activity in esophagus
0.15
-
activity in ileum and rectum
0.18
-
activity in esophagus and caecum, cofactor NADH
0.25
-
activity in forestomach and colon
0.3
-
activity in cytosol from mucous membrane of esophagus
0.5
-
activity in esophagus