1.7.1.B2: aromatic nitroreductase [NAD(P)H]
This is an abbreviated version!
For detailed information about aromatic nitroreductase [NAD(P)H], go to the full flat file.
Reaction
+
3 NAD(P)+
+
2 H2O
=
+
3 NAD(P)H
+
3 H+
Synonyms
NfnB, NfsB, NfsB_Ec, NfsB_Pa, NprA, oxygen-insensitive nitroreductase (NAD(P)H), YfkO
ECTree
Reaction
Reaction on EC 1.7.1.B2 - aromatic nitroreductase [NAD(P)H]
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an aromatic amine + 3 NAD(P)+ + 2 H2O = an aromatic nitrate + 3 NAD(P)H + 3 H+
an aromatic amine + NAD(P)+ + H2O = an aromatic hydroxylamine + NAD(P)H + H+
(1a)
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-
-
an aromatic hydroxylamine + NAD(P)+ = an aromatic nitric oxide + NAD(P)H + H+
(1b)
-
-
-
an aromatic nitric oxide + NAD(P)+ + H2O = an aromatic nitrate + NAD(P)H + H+
(1c)
-
-
-
an aromatic amine + 3 NAD(P)+ + 2 H2O = an aromatic nitrate + 3 NAD(P)H + 3 H+
(overall reaction)
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-
-
an aromatic amine + 3 NAD(P)+ + 2 H2O = an aromatic nitrate + 3 NAD(P)H + 3 H+
in vivo the reaction is obseverved in the opposite direction from that shown in the equation
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