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1.7.3.3: factor-independent urate hydroxylase

This is an abbreviated version!
For detailed information about factor-independent urate hydroxylase, go to the full flat file.

Word Map on EC 1.7.3.3

Reaction

Urate
+
O2
 +
H2O
=
5-hydroxyisourate
 +
H2O2

Synonyms

AaUO, AgUOX, dHU-wPU, ELITEK, Fasturtec, MVSM, N-35, Nodule specific uricase, Nodulin 35, Nodulin 35 homolog, Non-symbiotic uricase, oxidase, urate, Pucl, Rasburicase, Uaz, Uox, Urate oxidase, urate oxidoreductase, UriA, uric acid oxidase, uricase, uricase II, Uricoenzyme, Uricozyme

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.3 With oxygen as acceptor
                1.7.3.3 factor-independent urate hydroxylase

Temperature Range

Temperature Range on EC 1.7.3.3 - factor-independent urate hydroxylase

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TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
15 - 25
-
the enzyme is highly active in the range of 15-25°C. The enzyme loses approximately 35% of its original activity at temperatures over 35°C
20 - 50
20 - 55
-
20°C: about 80% of maximal activity, maximal activity at 30°C, 55°C: about 55% of maximal activity
20 - 70
-
free uricase shows at least 50% relative activity between 20 and 70°C
25 - 50
more than 50% activity between 25 and 50°C
35 - 60
-
-
40 - 45
-
the retained enzymatic activity at 40 and 45°C is 91.63% and 93.32%, respectively