1.7.5.1: nitrate reductase (quinone)
This is an abbreviated version!
For detailed information about nitrate reductase (quinone), go to the full flat file.
Word Map on EC 1.7.5.1
-
1.7.5.1
-
denitrification
-
denitrify
-
quinols
-
dissimilatory
-
chlorate
-
narj
-
narghji
-
molybdoenzyme
-
nitrate-reducing
-
menaquinol
-
nitrate-dependent
-
q-site
-
stigmatellin
-
menasemiquinone
-
hyscore
-
menadiol
- 1.7.5.1
-
denitrification
-
denitrify
- quinols
-
dissimilatory
- chlorate
- narj
-
narghji
-
molybdoenzyme
-
nitrate-reducing
- menaquinol
-
nitrate-dependent
-
q-site
- stigmatellin
-
menasemiquinone
-
hyscore
- menadiol
Reaction
Synonyms
EC 1.7.99.4, gene narH, membrane-bound nitrate reductase, membrane-bound quinol:nitrate oxidoreductase, MSMEG_5140, NaR, NaR1, NarG, NarGHI, narH, NarI, NarZ, nitrate reducatse A, nitrate reductase A, nitrate reductase Z, NRA nitrate reductase A, NRZ, NRZ nitrate reductase, Pden_4236, quinol-nitrate oxidoreductase, quinol/nitrate oxidoreductase, quinol:nitrate oxidoreductase, SCO6532, SCO6533, SCO6534, SCO6535
ECTree
Advanced search results
Metals Ions
Metals Ions on EC 1.7.5.1 - nitrate reductase (quinone)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Fe
Fe2+
Mo
Molybdenum
complete coordination of the four Fe-S centers of the beta-subunit from Escherichia coli nitrate reductase
Fe
-
coordination model for the four [Fe-S] centres of the electron-transfer subunit NarH, coordination scheme of the [Fe-S] clusters, functional role of [Fe-S] centres
Fe
cysteine arrangements typical of iron-sulfur centers are found in the NarH polypeptide. This suggests that the latter is an electron transfer unit of the nitrate reductase complex
Fe
domain I of subunit NarG holds the [4Fe-4S] cluster FS0. The coordination scheme of FS0 is: His50, Cys54, Cys58, Cys93. NarH contains three [4Fe-4S] clusters, FS1, FS2, FS3 and one [3Fe-4S] cluster, FS4
Fe
domain I of the catalytic subunit NadG holds the [4Fe-4S] cluster FS0
Fe
-
the 230000 Da complex contains 13 atoms iron and 12 atoms labile sulfur/molecules
Fe
-
the catalytic subunit of Escherichia coli nitrate reductase A contains a [4Fe-4S] cluster with a high-spin ground state
Fe
-
the four iron-sulfur centers of nitrate reductase A belong to two classes with markedly different redox potentials. The high-potential group comprises a [3Fe-4S] and a [4Fe-4S] cluster whose midpoint potentials are +60 mV and +80 mV, respectively. Although these centers are magnetically isolated, they are coupled by a significant anticooperative redox interaction of about 50 mV. The [4Fe-4S]1+ center occurs in two different conformations as shown by its composite EPR spectrum. The low-potential group contains two [4Fe-4S] clusters with more typical redox potentials (-200 mV and -400 mV). In the fully reduced state, the three [4Fe-4S]1+ centers are magnetically coupled. The iron-sulfur centers nitrate reductase Z and nitrate reductase A, exhibit essentially the same characteristics, except that the midpoint potentials of the high-potential centers of nitrate reductase Z appear negatively shifted by about 100 mV. A correspondence between the high-potential iron-sulfur clusters of the two enzymes can be proposed
Fe2+
the enzyme binds one [4Fe-4S] cluster per subunit
-
the enzyme contains a molybdenum cofactor. The enzyme-specific chaperone NarJ coordinates assembly and molybdenum cofactor acquisition of the heterotrimeric enzyme during the biogenesis process
Mo
the enzyme uses a molybdo-bis(molybdopterin guanine dinucleotide) cofactor for catalytic mechanism
Mo
-
the enzyme possesses a molybdopterin guanine dinucleotide active center. Two forms of the molybdenum center, high- and low-pH, are detectable by electron paramagnetic resonance spectroscopy
the enzyme contains one molybdenum-bis(molybdopterin guanine dinucleotide) cofactor per subunit
Molybdenum
the enzyme contains one molybdenum-bis(molybdopterin guanine dinucleotide) cofactor per subunit
Molybdenum
the enzyme contains one molybdenum-bis(molybdopterin guanine dinucleotide) cofactor per subunit