1.8.1.10: CoA-glutathione reductase
This is an abbreviated version!
For detailed information about CoA-glutathione reductase, go to the full flat file.
Reaction
Synonyms
CoA disulfide reductase, CoADR, CoASSG reductase, coenzyme A disulfide-glutathione reductase, coenzyme A glutathione disulfide reductase, EC 1.6.4.6, More, NADPH-dependent coenzyme A-SS-glutathione reductase, NADPH2:CoA-glutathione oxidoreductase, reductase, coenzyme A-glutathione disulfide
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Natural Substrates Products on EC 1.8.1.10 - CoA-glutathione reductase
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REACTION DIAGRAM
CoA + NADP+
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central role in thiol metabolism
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?
CoA disulfide + NADPH
CoA + NADP+
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central role in thiol metabolism
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?
glutathione + CoA + NADP+
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metabolism of CoA-glutathione disulfide, role may be to replenish the CoA pool from CoAS-SG formed either chemically or enzymatically during cell growth, accumulation of CoAS-SG in vivo in spite of high enzyme levels indicates involvement of a control mechanism
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?
CoA-glutathione + NADPH
glutathione + CoA + NADP+
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may be important in metabolism of CoASSG
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?