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1.8.1.12: trypanothione-disulfide reductase

This is an abbreviated version!
For detailed information about trypanothione-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.12

Reaction

trypanothione
+
NADP+
=
trypanothione disulfide
+
NADPH
+
H+

Synonyms

EC 1.6.4.8, LbTryR, LdTryR, Li-TryR, LiTR, N(1),N(8)-bis(glutathionyl)spermidine reductase, NADPH2:trypanothione oxidoreductase, TbTR, TCDM_11669, TcTR, TPR, TR, trypanothione disulfide reductase, trypanothione reductase, trypanothione-disulfide reductase, TryR

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.12 trypanothione-disulfide reductase

Sequence

Sequence on EC 1.8.1.12 - trypanothione-disulfide reductase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
TYTR_CRIFA
491
0
53229
Swiss-Prot
other Location (Reliability: 2)
TYTR_LEIDO
491
0
52933
Swiss-Prot
other Location (Reliability: 3)
TYTR_TRYBB
492
0
53284
Swiss-Prot
other Location (Reliability: 4)
TYTR_TRYCO
492
0
53443
Swiss-Prot
other Location (Reliability: 3)
TYTR_TRYCR
492
0
53868
Swiss-Prot
Secretory Pathway (Reliability: 5)
A0A3R7KSY2_9TRYP
490
0
53403
TrEMBL
other Location (Reliability: 3)
C6GKV5_LEIDO
491
0
53012
TrEMBL
other Location (Reliability: 3)
E9JUH4_LEIBR
483
0
52364
TrEMBL
other Location (Reliability: 3)
A0A0G3EHC9_LEIDO
491
0
53090
TrEMBL
other Location (Reliability: 2)
E9B8C5_LEIDB
Leishmania donovani (strain BPK282A1)
491
0
52993
TrEMBL
other Location (Reliability: 3)
A0A835JDS1_9ROSI
547
0
58955
TrEMBL
Mitochondrion (Reliability: 3)
A0A836KU40_9TRYP
491
0
52723
TrEMBL
other Location (Reliability: 3)
A0A7S1IX95_9EUGL
486
0
52075
TrEMBL
Mitochondrion (Reliability: 4)
A0A7S3KZT7_9STRA
512
0
54795
TrEMBL
other Location (Reliability: 3)
E9JUL2_LEIGU
483
0
52449
TrEMBL
other Location (Reliability: 3)
A0A3R7LYC7_TRYRA
644
0
72985
TrEMBL
other Location (Reliability: 2)
Q389T8_TRYB2
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
492
0
53157
TrEMBL
other Location (Reliability: 3)
A0A1E1INT4_LEIGU
491
0
53280
TrEMBL
other Location (Reliability: 3)
A4HSF7_LEIIN
491
0
53026
TrEMBL
other Location (Reliability: 3)
A0A0N1I1H2_LEPSE
491
0
53133
TrEMBL
other Location (Reliability: 2)
Q4CT43_TRYCC
Trypanosoma cruzi (strain CL Brener)
492
0
53869
TrEMBL
Secretory Pathway (Reliability: 5)
Q4CL55_TRYCC
Trypanosoma cruzi (strain CL Brener)
189
0
20442
TrEMBL
other Location (Reliability: 2)
V5AJG2_TRYCR
492
0
53888
TrEMBL
Secretory Pathway (Reliability: 5)
A4H480_LEIBR
491
0
53381
TrEMBL
other Location (Reliability: 3)
E9JUH3_LEIBR
483
0
52306
TrEMBL
other Location (Reliability: 3)
A0A0M9G2B3_9TRYP
491
0
53101
TrEMBL
other Location (Reliability: 2)
A0A3L6KZJ1_9TRYP
492
0
53157
TrEMBL
other Location (Reliability: 3)
E9JUG6_LEIBR
483
0
52420
TrEMBL
other Location (Reliability: 3)
A0A2D9SFG1_9PROT
449
0
48972
TrEMBL
-
G0UXJ3_TRYCI
Trypanosoma congolense (strain IL3000)
492
0
53396
TrEMBL
other Location (Reliability: 3)
W6L5G2_9TRYP
491
0
53727
TrEMBL
other Location (Reliability: 3)
A0A3S7WP12_LEIDO
491
0
52993
TrEMBL
other Location (Reliability: 3)
A0A837A9I2_9TRYP
491
0
52975
TrEMBL
other Location (Reliability: 2)
A0A3R7NB58_TRYRA
490
0
53503
TrEMBL
other Location (Reliability: 3)
A0A2D7KUG2_9PROT
450
0
49736
TrEMBL
-
A0A061J4G2_TRYRA
490
0
53574
TrEMBL
other Location (Reliability: 3)
Q4QJG7_LEIMA
491
0
53144
TrEMBL
other Location (Reliability: 2)
A0A5P8JH73_9RHOB
466
0
49753
TrEMBL
-
A0A1X0P0G9_9TRYP
491
0
53385
TrEMBL
other Location (Reliability: 4)
A0A836KUF5_9TRYP
491
0
53265
TrEMBL
other Location (Reliability: 2)
Q0GU43_LEIAM
476
0
51365
TrEMBL
other Location (Reliability: 3)
E9JUH9_LEIBR
483
0
52392
TrEMBL
other Location (Reliability: 3)
E9JUJ6_LEIGU
483
0
52448
TrEMBL
other Location (Reliability: 3)
A0A7G2CTA5_9TRYP
489
0
53026
TrEMBL
other Location (Reliability: 2)
U3LNC3_9TRYP
492
0
53110
TrEMBL
other Location (Reliability: 4)
A0A836IY73_9TRYP
490
0
53137
TrEMBL
other Location (Reliability: 2)
A0A0L1KJW7_9EUGL
511
0
55761
TrEMBL
other Location (Reliability: 5)
A0A6L0WLV7_LEIIN
491
0
53026
TrEMBL
other Location (Reliability: 3)
W6KQF0_9TRYP
491
0
53177
TrEMBL
other Location (Reliability: 3)
G0U7X7_TRYVY
Trypanosoma vivax (strain Y486)
492
0
53804
TrEMBL
other Location (Reliability: 3)
A5JV95_LEIAM
491
0
53103
TrEMBL
other Location (Reliability: 2)
E9JUK3_LEIGU
483
0
52374
TrEMBL
other Location (Reliability: 3)
A0A0S4J6A3_BODSA
494
0
53326
TrEMBL
other Location (Reliability: 5)
A0A2V2X955_TRYCR
492
0
53868
TrEMBL
Secretory Pathway (Reliability: 5)
E9JUI7_LEIGU
483
0
52421
TrEMBL
other Location (Reliability: 3)
A0A7S1FVP8_9STRA
509
0
55286
TrEMBL
Mitochondrion (Reliability: 2)
S9V396_9TRYP
491
0
52907
TrEMBL
other Location (Reliability: 2)
A0A088RI55_9TRYP
491
0
53309
TrEMBL
other Location (Reliability: 3)
E9JUG5_LEIBR
483
0
52378
TrEMBL
other Location (Reliability: 3)
A0A7S4L7B8_9EUKA
501
0
54865
TrEMBL
Secretory Pathway (Reliability: 5)
D0A4H8_TRYB9
Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)
492
0
53157
TrEMBL
other Location (Reliability: 3)
A0A3P3YXN3_LEIBR
491
0
53381
TrEMBL
other Location (Reliability: 3)
Q26970_TRYCR
453
0
49417
TrEMBL
other Location (Reliability: 3)
A0A837AYC7_9TRYP
491
0
53223
TrEMBL
other Location (Reliability: 2)
A0A422QAS6_9TRYP
644
0
72842
TrEMBL
other Location (Reliability: 1)
A0A1G4I7S0_TRYEQ
492
0
53157
TrEMBL
other Location (Reliability: 3)
A0A2V2UK30_TRYCR
492
0
53937
TrEMBL
Secretory Pathway (Reliability: 5)
A0A1X7KS90_9RHOB
466
0
49753
TrEMBL
-
B0ECF4_ENTDS
Entamoeba dispar (strain ATCC PRA-260 / SAW760)
409
0
46561
TrEMBL
other Location (Reliability: 1)
A0A836H3P8_LEIEN
491
0
53231
TrEMBL
other Location (Reliability: 3)
E9AKE1_LEIMU
Leishmania mexicana (strain MHOM/GT/2001/U1103)
491
0
53174
TrEMBL
other Location (Reliability: 2)
A0A2V2VRK4_TRYCR
492
0
53888
TrEMBL
Secretory Pathway (Reliability: 5)
A0A640KDF2_LEITA
491
0
53106
TrEMBL
other Location (Reliability: 2)
Q8MZR8_ENTHI
394
0
43558
TrEMBL
-
Q95PT6_LEIDO
491
0
53930
TrEMBL
-
TYTR_TRYCR
492
0
53868
Swiss-Prot
Secretory Pathway (Reliability: 4)
TYTR_CRIFA
491
0
53229
Swiss-Prot
-