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1.8.1.7: glutathione-disulfide reductase

This is an abbreviated version!
For detailed information about glutathione-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.7

Reaction

2 glutathione +

NADP+
=
glutathione disulfide
+
NADPH
+
H+

Synonyms

At3g54660, EC 1.6.4.2, GLR, glutahione reductase, glutathione disulfide reductase, glutathione reductase, glutathione reductase (NADPH), glutathione reductase 3, glutathione reductase Glr1, glutathione S-reductase, glutathione: NADP(+) oxidoreductase, glutathione: NADP+ oxidoreductase, glutathione:NADP+ oxidoreductase, Gor, GOR1, GOR2, GR, GR1, GR2, Gr3, GRase, GRase-1, GRd, GSH reductase, GSHR, Gsr, GSR-1, GSSG reductase, HCOI_01258400, hGR, HvGR1, HvGR2, multifunctional thioredoxin-glutathione reductase, NADPH-glutathione reductase, NADPH-GSSG reductase, NADPH-reduced GR, NADPH: oxidized glutathione oxidoreductase, NADPH:oxidized glutathione oxidoreductase, NADPH:oxidized-glutathione oxidoreductase, OBP29, PfGR, psgr, PtGR1.1, PtGR1.2, PtGR2, reductase, glutathione, SpGR, TaGR1, TaGR2, TGR, thioredoxin glutathione reductase, thioredoxin/glutathione reductase, TrxR3

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.7 glutathione-disulfide reductase

Source Tissue

Source Tissue on EC 1.8.1.7 - glutathione-disulfide reductase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
low enzyme activity
Manually annotated by BRENDA team
-
glutathione reductase activity is significantly lower in leprosy as compared to the control group
Manually annotated by BRENDA team
-
mature kernel endosperm, 2 isoforms belonging to different developmental stages
Manually annotated by BRENDA team
-
doxorubicin-sensitive lung cancer cell line
Manually annotated by BRENDA team
-
doxorubicin-insensitive lung cancer cell line expressing the MRP multi-drug resistant protein
Manually annotated by BRENDA team
-
doxorubicin-insensitive leukemic cell line HL-60-R, a subclone of HL-60
Manually annotated by BRENDA team
-
i.e. cysticeri, recovered from peritoneal cavity of 6-8 months before inoculated female Balb/c mice
Manually annotated by BRENDA team
-
localization of the enzyme in pancreatic tissue, overview
Manually annotated by BRENDA team
-
pancreas, lower expression level than in islet cells
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
doxorubicin-sensitive lung cancer cell line
Manually annotated by BRENDA team
-
doxorubicin-insensitive lung cancer cell line expressing the MRP multi-drug resistant protein
Manually annotated by BRENDA team
additional information