highest mRNA expression of mitochondrial isoform of Liza haematocheila glutathione reductase is observed in the gill tissue under normal physiological conditions
tubule and cortex, developmental changes in enzyme activity from fetal prenatal over neonatal to adult stage, overview, gradual increase with maximum at adult age
the early decrease of glutathione reductase activity in leaves treated with polyamines can be due to a direct interaction of these compounds with the enzyme
glutathione reductase plays a key role in maintaining thiol groups in the lens, and its activity decreases with aging and cataract formation. The glutathione reductase activity in the cortex and nucleus of the cataractous lenses is significantly lower than that of the aged clear lenses. The highest activity in the cortex is observed in the clear aged lenses. The combination of thioredoxin and thioredoxin reductase revives the activity of glutathione reductase from both the cortex and nucleus of aged clear lenses. In cataract lenses (grade II and grade IV), there is a statistically significant recovery of glutathione reductase activity in the cortex, but not in the nucleus. No recovery is observed when thioredoxin or thioredoxin reductase are used separately. alpha-Crystallin successfully revives glutathione reductase activity in the cortex of cataract grade II lenses, but not in the nucleus. The combination of alpha-crystallin and thioredoxin/thioredoxin reductase gives a further increase of activity. Thioltransferase alone revives some of the glutathione reductase activity but together with the thioredoxin/thioredoxin reductase system gives no statistically significant enhancement of glutathione reductase activity
the combination of thioredioxin and thioredoxin reductase revives the activity of glutathione reductase from both the cortex and nucleus of aged clear lenses. In cataract lenses (grade II and grade IV) there is a statistically significant recovery of glutathione reductase activity in the cortex, but not in the nucleus. alpha-Crystallin successfully revives glutathione reductase activity in the cortex of cataract grade II lenses, but not in the nucleus. the combination of alpha-crystallin and thioredoxin/thioredoxin reductase gives a further increase in activity. Both disulfide bond formation and protein unfolding are responsible for glutathione inactivation
mainly in epithelium, low content in alveoli, developmental changes in enzyme activity from fetal prenatal over neonatal to adult stage, overview, substantially constant
HvGR2 is mainly expressed in root tissue. HvGR2 is upregulated in response to Fe-deficiency. Glutathione reductase is not post-transcriptionally regulated
TaGR2 is mainly expressed in root tissue. TaGR2 is upregulated in response to Fe-deficiency. Glutathione reductase is not post-transcriptionally regulated
HvGR1 is mainly expressed in shoot tissue. HvGR1 is upregulated in response to Fe-deficiency. Glutathione reductase is not post-transcriptionally regulated