1.8.4.10: adenylyl-sulfate reductase (thioredoxin)

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For detailed information about adenylyl-sulfate reductase (thioredoxin), go to the full flat file.

Word Map on EC 1.8.4.10

1.8.4.10

aeruginosa

sulfur

thioredoxins

reductases

gamma-glutamylcysteine

physcomitrella

moss

thiosulfate

assimilatory

patens

two-electron

analysis

Reaction

Synonyms

5'-adenylylsulfate reductase, adenosine-5'-phosphosulfate reductase, adenylylsulfate reductase, APR, APR-B, APS reductase, PaAPR, PpAPR-B, thioredoxin dependent 5'-adenylylsulfate reductase, thioredoxin-dependent APS reductase

ECTree

1 Oxidoreductases

1.8 Acting on a sulfur group of donors

1.8.4 With a disulfide as acceptor

1.8.4.10 adenylyl-sulfate reductase (thioredoxin)

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Results	in table
1	Activating Compound
17096	AA Sequence
1	Application
1	CAS Registry Number
7	Cloned(Commentary)
22	Cofactor
2	Crystallization (Commentary)
1	General Stability
7	Inhibitors
7	kcat/KM [mM/s]
1	Ki Value [mM]
17	KM Value [mM]
9	Metals/Ions
6	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
32	Organism
1	Pathway
10	PDB ID
4	pH Optimum
1	pH Stability
8	Protein Variants
4	Purification (Commentary)
2	Reaction
3	Reaction Type
31	Reference
1	Source Tissue
2	Storage Stability
52	Substrates and Products (Substrate)
4	Subunits
17	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
9	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.8.4.10 - adenylyl-sulfate reductase (thioredoxin)

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2-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-[(2-sulfanylethyl)amino]-9H-purin-9-yl]oxolan-2-yl]ethyl phosphate

Mycobacterium tuberculosis

best inhibitor analyzed. The S atom is capable of establishing favorable interactions with the Fe-S cluster

743374

5'-AMP

2 entries

adenosine-5'-phosphosulfate

Pseudomonas aeruginosa

O05927

393947

additional information

3 entries