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1.8.4.2: protein-disulfide reductase (glutathione)

This is an abbreviated version!
For detailed information about protein-disulfide reductase (glutathione), go to the full flat file.

Word Map on EC 1.8.4.2

Reaction

2 glutathione +

protein-disulfide
=
glutathione-disulfide
+
protein-dithiol

Synonyms

BbdC, BdbD, C1orf31, CatA protein, ccdA associated thiol-disulfide oxidoreductase, COA6, DcbA, desulfothioredoxin, DIP1880, disulfide bond-forming thiol-disulfide oxidoreductase, disulphide interchange enzyme, DsbA, DsbA1, DsbA2, Dtrx, ERp57, GIT, glutathione-insulin transhydrogenase, glutathione-protein disulfide oxidoreductase, GRX1, GRX2, GRX3, GRX5, GRX6, GrxS12, GSH-dependent protein disulfide oxidoreductase, GSH-insulin transhydrogenase, HP_0231, insulin reductase, mcrophage migration inhibitory factor-2, MdbA, MdbACm, membrane-bound thiol-disulfide oxidoreductase, Mif-2, More, protein disulfide reductase (glutathione), protein disulfide transhydrogenase, protein-disulfide interchange enzyme, protein-disulfide isomerase/oxidoreductase, RCAP_rcc01743, reductase, protein disulfide (glutathione), ResA, SdbA, SGO_2006, SpyM18_2037, StoA, Streptococcus disulfide bond protein A, TDOR, thiol disulfide oxidoreductase, thiol-disulfide oxidoreductase, thiol-protein disulphide oxidoreductase, thiol:disulfide oxidoreductase, thiol:protein-disulfide oxidoreductase, WhiB1, WhiB1/Rv3219, YkuV, YMR244C-A

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.2 protein-disulfide reductase (glutathione)

Natural Substrates Products

Natural Substrates Products on EC 1.8.4.2 - protein-disulfide reductase (glutathione)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2 glutathione + COX2-disulfide
glutathione-disulfide + COX2-dithiol
show the reaction diagram
2 glutathione + pilin FimA-disulfide
glutathione-disulfide + pilin FimA-dithiol
show the reaction diagram
2 glutathione + protein AtlS-disulfide
glutathione-disulfide + protein AtlS-dithiol
show the reaction diagram
2 glutathione + protein-disulfide
glutathione-disulfide + protein-dithiol
show the reaction diagram
2 glutathione + SCO1-disulfide
glutathione-disulfide + SCO1-dithiol
show the reaction diagram
2 glutathione + SCO2-disulfide
glutathione-disulfide + SCO2-dithiol
show the reaction diagram
-
-
-
?
GSH + AtlS
GSSG + ?
show the reaction diagram
-
-
-
-
?
GSH + protein disulfide
GSSG + protein-dithiol
show the reaction diagram
GSH + protein-disulfide
GSSG + protein-dithiol
show the reaction diagram
SdbA carrying a disulfide bond + superantigen SpeA with reduced L-cysteine residues
SdbA with reduced L-cysteine residues + superantigen SpeA carrying a disulfide bond
show the reaction diagram
-
-
-
-
?
additional information
?
-