1.8.4.2: protein-disulfide reductase (glutathione)

This is an abbreviated version!
For detailed information about protein-disulfide reductase (glutathione), go to the full flat file.

Word Map on EC 1.8.4.2

1.8.4.2

tautomerase

glutaredoxins

insulin-degrading

d-dopachrome

5.3.4.1

dsbas

whib-like

thioredoxin-like

125i-insulin

disulphide-isomerase

medicine

Reaction

2 glutathione +

Synonyms

BbdC, BdbD, C1orf31, CatA protein, ccdA associated thiol-disulfide oxidoreductase, COA6, DcbA, desulfothioredoxin, DIP1880, disulfide bond-forming thiol-disulfide oxidoreductase, disulphide interchange enzyme, DsbA, DsbA1, DsbA2, Dtrx, ERp57, GIT, glutathione-insulin transhydrogenase, glutathione-protein disulfide oxidoreductase, GRX1, GRX2, GRX3, GRX5, GRX6, GrxS12, GSH-dependent protein disulfide oxidoreductase, GSH-insulin transhydrogenase, HP_0231, insulin reductase, mcrophage migration inhibitory factor-2, MdbA, MdbACm, membrane-bound thiol-disulfide oxidoreductase, Mif-2, More, protein disulfide reductase (glutathione), protein disulfide transhydrogenase, protein-disulfide interchange enzyme, protein-disulfide isomerase/oxidoreductase, RCAP_rcc01743, reductase, protein disulfide (glutathione), ResA, SdbA, SGO_2006, SpyM18_2037, StoA, Streptococcus disulfide bond protein A, TDOR, thiol disulfide oxidoreductase, thiol-disulfide oxidoreductase, thiol-protein disulphide oxidoreductase, thiol:disulfide oxidoreductase, thiol:protein-disulfide oxidoreductase, WhiB1, WhiB1/Rv3219, YkuV, YMR244C-A

ECTree

1 Oxidoreductases

1.8 Acting on a sulfur group of donors

1.8.4 With a disulfide as acceptor

1.8.4.2 protein-disulfide reductase (glutathione)

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
32	Activating Compound
843	AA Sequence
1	Application
1	CAS Registry Number
23	Cloned(Commentary)
6	Crystallization (Commentary)
45	Disease/ Diagnostics
76	General Information
8	General Stability
101	Inhibitors
5	kcat/KM [mM/s]
2	Ki Value [mM]
51	KM Value [mM]
44	Localization
5	Metals/Ions
32	Molecular Weight [Da]
73	Natural Substrates/ Products (Substrates)
164	Organism
2	Pathway
31	PDB ID
14	pH Optimum
4	pH Range
5	Posttranslational Modification
47	Protein Variants
32	Purification (Commentary)
15	Reaction
3	Reaction Type
146	Reference
127	Source Tissue
38	Specific Activity [micromol/min/mg]
2	Storage Stability
313	Substrates and Products (Substrate)
30	Subunits
160	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
5	Temperature Stability [°C]
11	Turnover Number [1/s]

Purification

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Purification on EC 1.8.4.2 - protein-disulfide reductase (glutathione)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Purification (commentary) Search

6 entries

anion-exchange chromatography (DEAE) and gel filtration (Superdex 75)

Bacillus subtilis

669523

Ni2+-NTA affinity chromatography

Mycobacterium tuberculosis

670797

nickel-nitrilotriacetic acid column chromatography

Desulfovibrio vulgaris

725470

partially

Bos taurus

3052, 394835, 394839

recombiant GST-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by glutathione affinity chromatography and gel filtration

Homo sapiens

Q5JTJ3

764441

recombiant His-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and gel filtration

Saccharomyces cerevisiae

Q3E846

764441

recombinant enzyme

2 entries

recombinant enzyme from periplasm

Escherichia coli

394861

recombinant N-terminally His6-tagged wild-type and mutant enzymes from Escherichia coli strain XL-1 Blue by nickel affinity chromatography

2 entries

recombinant wild-type and mutant enzymes

Homo sapiens

394863