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2.1.1.128: (RS)-norcoclaurine 6-O-methyltransferase

This is an abbreviated version!
For detailed information about (RS)-norcoclaurine 6-O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.128

Reaction

S-adenosyl-L-methionine
+
(RS)-norcoclaurine
=
S-adenosyl-L-homocysteine
 +
(RS)-coclaurine

Synonyms

(R,S)-norcoclaurine 6-O-methyltransferase, (S)-Coclaurine N-methyltransferase, (S)-norcoclaurine 6-O-methyltransferase, (S)-norcoclaurine-6-O-methyltransferase, 3’-hydroxy-N-methylcoclaurine 4’-O-methyltransferase, 6-OMT, 6OMT, 6OMT1, 6OMT2, 7OMT, Ec4’OMT, Methyltransferase, (S)-coclaurine N-, Methyltransferase, norlaudanosoline, NLS-OMT, Norcoclaurine 6-O-methyltransferase, Ps6OMT, S-Adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase, S-Adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase, S-Adenosylmethionine:(R),(S)-norlaudanosoline-6-O-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.128 (RS)-norcoclaurine 6-O-methyltransferase

Expression

Expression on EC 2.1.1.128 - (RS)-norcoclaurine 6-O-methyltransferase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
enzyme expression is upregulated in the high papaverine mutant pap1
the over-expression of regulatory factors AP2G, AN1-like, ERF2, GARP, MDB025 and WRKY1 increases the levels of codeinone reductase, (S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase) and (R,S)-norcoclaurine 6-O-methyltransferase transcripts by 10- to more than 100fold. The transcriptional activations translate into an enhancement of alkaloid production in opium poppy of up to at least 10fold
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