2.1.1.132: precorrin-6B C5,15-methyltransferase (decarboxylating) This is an abbreviated version! For detailed information about precorrin-6B C5,15-methyltransferase (decarboxylating), go to the full flat file .
Reaction
2 S-adenosyl-L-methionine
+
precorrin-6B =
2 S-adenosyl-L-homocysteine
+
precorrin-8X +
CO2
Synonyms CobL, GenBank L12005-derived protein, Genbank L12006-derived protein, GenBank U67594-derived protein GI 1500413, Gene cbiE precorrin 6y methylase, Gene cbiT precorrin methylase, Methyltransferase precorrin 6y (Salmonella typhimurium strain LT2 gene cbiE), methyltransferase, precorrin 6y, Methyltransferase, precorrin 6y (Methanococcus jannaschii), Methyltransferase, precorrin 6y (Salmonella typhimurium strain LT2 gene cbiT), Precorrhin-6y methyltransferase, Precorrin-6 methyltransferase, Precorrin-6Y methylase, precorrin-6y methyltransferase, precorrin-8w decarboxylase, Protein (Salmonella typhimurium clone pJO gene cbiE reduced), Protein (Salmonella typhimurium clone pJO26 gene cbiT reduced)
ECTree
Natural Substrates Products
Natural Substrates Products on EC 2.1.1.132 - precorrin-6B C5,15-methyltransferase (decarboxylating)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Adenosyl-L-methionine + precorrin-6Y
?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
additional information
?
-
Adenosyl-L-methionine + precorrin-6Y
?
-
enzyme of the vitamin B12 biosynthetic pathway
-
-
?
Adenosyl-L-methionine + precorrin-6Y
?
-
enzyme of the cobalamin biosynthetic pathway
-
-
?
Adenosyl-L-methionine + precorrin-6Y
?
-
enzyme of the cobalamin biosynthetic pathway
-
-
?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
steps of the cobalamin, i.e. vitamin B12, biosynthesis, pathway overview
-
-
?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
methylation and decarboxylation are catalyzed by 2 different enzymes in Propionibacterium freudenreichii, encoded by gene cbiE, organized in a orf/single gene with cbiG and cbiH, which is responsible for the methylations at C5 and C15, and by gene cbiT, which is responsible for the decarboxylation, steps of the anaerobic cobalamin biosynthesis, pathway overview
-
-
?
S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
-
steps of the aerobic cobalamin biosynthesis, pathway overview
-
-
?
additional information
?
-
-
evolutionary origin of the cbiT
-
-
?
additional information
?
-
-
the organism performs the anaerobic cobalamin biosynthesis variant, the gene cbiE of Propionibacterium freudenreichii is organized in a single ORF with genes cbiH and cbiG, overview
-
-
?
additional information
?
-
-
the organism performs the aerobic cobalamin biosynthesis variant
-
-
?