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2.1.1.160: caffeine synthase

This is an abbreviated version!
For detailed information about caffeine synthase, go to the full flat file.

Word Map on EC 2.1.1.160

Reaction

S-adenosyl-L-methionine
+
1,7-dimethylxanthine
=
S-adenosyl-L-homocysteine
+
1,3,7-Trimethylxanthine

Synonyms

1-N-methyltransferase, 1NMT, 3, 7-dimethylxanthine methyltransferase, 3,7-dimethylxanthine methyltransferase, 7-N-methylxanthine methyltransferase, caffeine synthase, caffeine synthase 1, CCS, CCS1, coffee caffeine synthase 1, CS, CtCS6, DXMT, DXMT1, N-1 methyltransferase, TCS, TCS1, tea caffeine synthase, tea caffeine synthase 1, theobromine 1-N-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.160 caffeine synthase

Inhibitors

Inhibitors on EC 2.1.1.160 - caffeine synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-chloromercuribenzoate
-
complete inhibition at 0.5 mM, 23% inhibition at 0.05 mM
azouracil
-
18% inhibition at 0.1 mM, no inhibition at 1 mM
iodoacetate
-
complete inhibition at 100 mM, 89% inhibition at 10 mM
KCN
-
74% inhibition at 100 mM, but 33% activation at 10 mM
N-Methylmaleimide
-
complete inhibition at 1 mM, no inhibition at 0.1 mM
NaN3
-
22% inhibition at 10 mM, 16% at 1 mM
additional information
-
no inhibition by EDTA at 0.5-5 mM
-