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2.1.1.165: methyl halide transferase

This is an abbreviated version!
For detailed information about methyl halide transferase, go to the full flat file.

Word Map on EC 2.1.1.165

Reaction

S-adenosyl-L-methionine
+
Iodide
=
S-adenosyl-L-homocysteine
+
methyl iodide

Synonyms

AtHOL1, AtHOL2, AtHOL3, halide/bisulfide methyltransferase, HMT, HMT/HTMT, HOL, HTMT, MCT, methyl chloride transferase, methyl halide transferase, MHT, S-adenosyl-L-methionine: halide ion methyltransferase, S-adenosyl-L-methionine:halide/bisulfide methyltransferase, S-adenosylmethionine-dependent halide/thiol methyltransferase, SAM:halide ion methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.165 methyl halide transferase

Inhibitors

Inhibitors on EC 2.1.1.165 - methyl halide transferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
1 mM, 16% inhibition, production of methyl iodide
bisulfide
-
-
chloride
competitive inhibition of methyl iodide formation
CN-
-
100 mM, complete inhibition, production of methyl iodide
CoCl2
-
1 mM, 18% inhibition, production of methyl iodide
dithiothreitol
-
5 mM, 28% inhibition, production of methyl iodide
EDTA
-
5 mM, 32% inhibition, production of methyl iodide
HS-
-
10 mM, 84% inhibition, production of methyl iodide
Iodide
-
above 25 mM
MgSO4
-
1 mM, 25% inhibition, production of methyl iodide
monoiodoacetate
-
5 mM, 28% inhibition, production of methyl iodide
NaN3
-
5 mM, 32% inhibition, production of methyl iodide
NiCl2
-
1 mM, 38% inhibition, production of methyl iodide
PCMB
-
0.5 mM, 30% inhibition, production of methyl iodide
S-adenosyl-L-homocysteine
SCN-
-
10 mM, 60% inhibition, production of methyl iodide
ZnCl2
-
1 mM, 14% inhibition, production of methyl iodide
additional information
-
activity is not inhibited by high iodide concentrations
-