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2.1.1.167: 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase

This is an abbreviated version!
For detailed information about 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.167

Reaction

S-adenosyl-L-methionine
+
guanosine2922 in 27S pre-rRNA
=
S-adenosyl-L-homocysteine
+
2'-O-methylguanosine2922 in 27S pre-rRNA

Synonyms

Spb1p

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.167 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase

Engineering

Engineering on EC 2.1.1.167 - 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D52A
-
when the mutant protein is the sole source of Spb1p in the cell (strain YBL4637), it leads to a severe growth defect with a generation time of about 300 min. No formation of 2'-O-methylguanosine2922
additional information