2.1.1.168: 21S rRNA (uridine2791-2'-O)-methyltransferase

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For detailed information about 21S rRNA (uridine2791-2'-O)-methyltransferase, go to the full flat file.

Reaction

Synonyms

mitochondrial 21S rRNA methyltransferase, mitochondrial rRNA MTase 2, MRM2

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.168 21S rRNA (uridine2791-2'-O)-methyltransferase

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4	AA Sequence
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1	Natural Substrates/ Products (Substrates)
2	Organism
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Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.168 - 21S rRNA (uridine2791-2'-O)-methyltransferase

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S-adenosyl-L-methionine + uridine2791 in 21S rRNA

S-adenosyl-L-homocysteine + 2'-O-methyluridine2791 in 21S rRNA

Saccharomyces cerevisiae

P53123

mitochondria of the yeast Saccharomyces cerevisiae assemble their ribosomes from ribosomal proteins, encoded by the nuclear genome (with one exception), and rRNAs of 15S and 21S, encoded by the mitochondrial genome. Unlike cytoplasmic rRNA, which is highly modified, mitochondrial rRNA contains only three modified nucleotides: a pseudouridine and two 2'-O-methylated riboses (Gm2270 and Um2791) located at the peptidyl transferase centre of 21S rRNA. Mrm2 is required for methylating U2791 of 21S rRNA

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