2.1.1.173: 23S rRNA (guanine2445-N2)-methyltransferase

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For detailed information about 23S rRNA (guanine2445-N2)-methyltransferase, go to the full flat file.

Reaction

Synonyms

23S RNA m(2)G2445 methyltransferase, EC 2.1.1.51, EC 2.1.1.52, m2G2445 methyltransferase, ribosomal large subunit methyltransferase, RlmKL, RlmL, Smu472, ycbY

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.173 23S rRNA (guanine2445-N2)-methyltransferase

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Results	in table
7991	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
4	Cofactor
1	Crystallization (Commentary)
10	General Information
1	Metals/Ions
4	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
8	Organism
4	PDB ID
1	pH Optimum
2	Protein Variants
2	Purification (Commentary)
1	Reaction
8	Reference
18	Substrates and Products (Substrate)
6	Subunits
20	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.1.1.173 - 23S rRNA (guanine2445-N2)-methyltransferase

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SYSTEMATIC NAME

IUBMB Comments

S-adenosyl-L-methionine:23S rRNA (guanine2445-N2)-methyltransferase

The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine2445 at N2 in 23S rRNA.