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2.1.1.183: 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase

This is an abbreviated version!
For detailed information about 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase, go to the full flat file.

Word Map on EC 2.1.1.183

Reaction

4 S-adenosyl-L-methionine +

adenine1779/adenine1780 in 18S rRNA
= 4 S-adenosyl-L-homocysteine +
N6-dimethyladenine1779/N6-dimethyladenine1780 in 18S rRNA

Synonyms

18S rRNA dimethylase Dim1p, DIM1, Dim1p, EC 2.1.1.48, KIDIM1, m2(6)A dimethylase, ScDim1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.183 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase

Reference

Reference on EC 2.1.1.183 - 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lafontaine, D.; Vandenhaute, J.; Tollervey, D.
The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast
Genes Dev.
9
2470-2481
1995
Saccharomyces cerevisiae (C7GSG6), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Lafontaine, D.; Delcour, J.; Glasser, A.L.; Desgres, J.; Vandenhaute, J.
The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast
J. Mol. Biol.
241
492-497
1994
Saccharomyces cerevisiae (C7GSG6)
Manually annotated by BRENDA team
Pulicherla, N.; Pogorzala, L.A.; Xu, Z.; O'Farrell, H.C.; Musayev, F.N.; Scarsdale, J.N.; Sia, E.A.; Culver, G.M.; Rife, J.P.
Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases
J. Mol. Biol.
391
884-893
2009
Saccharomyces cerevisiae (C7GSG6)
Manually annotated by BRENDA team
Lafontaine, D.L.; Preiss, T.; Tollervey, D.
Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?
Mol. Cell. Biol.
18
2360-2370
1998
Saccharomyces cerevisiae (C7GSG6), Saccharomyces cerevisiae
Manually annotated by BRENDA team
O'Farrell, H.C.; Pulicherla, N.; Desai, P.M.; Rife, J.P.
Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution
RNA
12
725-733
2006
Saccharomyces cerevisiae (C7GSG6)
Manually annotated by BRENDA team
Housen, I.; Demonte, D.; Lafontaine, D.; Vandenhaute, J.
Cloning and characterization of the KlDIM1 gene from Kluyveromyces lactis encoding the m2(6)A dimethylase of the 18S rRNA
Yeast
13
777-781
1997
Kluyveromyces lactis (P78697), Kluyveromyces lactis
Manually annotated by BRENDA team