2.1.1.188: 23S rRNA (guanine748-N1)-methyltransferase
This is an abbreviated version!
For detailed information about 23S rRNA (guanine748-N1)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.188
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2.1.1.188
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rrnas
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macrolide
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fradiae
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methyltransferases
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stem-loops
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dimethyltransferase
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streptogramin
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footprint
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lincosamide
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exit
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telithromycin
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16-membered
- 2.1.1.188
- rrnas
-
macrolide
- fradiae
- methyltransferases
-
stem-loops
-
dimethyltransferase
-
streptogramin
-
footprint
-
lincosamide
-
exit
- telithromycin
-
16-membered
Reaction
Synonyms
methyltransferase RlmAII, RlmA II, RlmA(II), RlmAII, rRNA large subunit methyltransferase II, TlrB, tylosin resistance methyltransferase RlmA(II), tylosin-resistance methyltransferase RlmA(II)
ECTree
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General Information
General Information on EC 2.1.1.188 - 23S rRNA (guanine748-N1)-methyltransferase
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malfunction
metabolism
physiological function
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the inactivation of the enzyme confers telithromycin resistance
malfunction
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the inactivation of the enzyme confers telithromycin resistance
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the enzyme enhances binding of telithromycin to A752 in ribosomes
metabolism
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the enzyme enhances binding of telithromycin to A752 in ribosomes
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methylation of 23S rRNA nucleotide G748 by RlmAII methyltransferase renders Streptococcus pneumoniae telithromycin susceptible
physiological function
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methylation of 23S rRNA nucleotide G748 by RlmAII methyltransferase renders Streptococcus pneumoniae telithromycin susceptible
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