2.1.1.195: cobalt-precorrin-5B (C1)-methyltransferase
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For detailed information about cobalt-precorrin-5B (C1)-methyltransferase, go to the full flat file.
Reaction
Synonyms
CbiD, cobalt-precorrin-6A synthase
ECTree
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Application
Application on EC 2.1.1.195 - cobalt-precorrin-5B (C1)-methyltransferase
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synthesis
coexpression of the cobA gene from Propionibacterium freudenreichii and the cbiA, -C, -D, -E, -T, -F, -G, -H, -J, -K, -L, and -P genes from Salmonella enterica serovar typhimurium in Escherichia coli result in the production of cobyrinic acid a,c-diamide. A cbiD deletion mutant of this strain produces 1-desmethylcobyrinic acid a,c-diamide, indicating that CbiD is involved in C-1 methylation in the anaerobic pathway to cobalamin