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2.1.1.196: cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]

This is an abbreviated version!
For detailed information about cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating], go to the full flat file.

Reaction

cobalt-precorrin-6B
+
S-adenosyl-L-methionine
+
H+
=
cobalt-precorrin-7
+
S-adenosyl-L-homocysteine
+
CO2

Synonyms

CbiE, CbiT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.196 cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]

Systematic Name

Systematic Name on EC 2.1.1.196 - cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]

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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:precorrin-6B C15-methyltransferase (C-12-decarboxylating)
This enzyme, which participates in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway, catalyses both methylation at C-15 and decarboxylation of the C-12 acetate side chain of cobalt-precorrin-6B. The equivalent activity in the aerobic adenosylcobalamin biosynthesis pathway is catalysed by the bifunctional enzyme EC 2.1.1.132, precorrin-6B C5,15-methyltransferase (decarboxylating).