2.1.1.196: cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]
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For detailed information about cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating], go to the full flat file.
Reaction
Synonyms
CbiE, CbiT
ECTree
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Systematic Name
Systematic Name on EC 2.1.1.196 - cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]
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S-adenosyl-L-methionine:precorrin-6B C15-methyltransferase (C-12-decarboxylating)
This enzyme, which participates in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway, catalyses both methylation at C-15 and decarboxylation of the C-12 acetate side chain of cobalt-precorrin-6B. The equivalent activity in the aerobic adenosylcobalamin biosynthesis pathway is catalysed by the bifunctional enzyme EC 2.1.1.132, precorrin-6B C5,15-methyltransferase (decarboxylating).